Suzuki T - Search Results

1

Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis.

Wu X, Fang Z, Yang B, Zhong L, Yang Q, Zhang C, Huang S, Xiang R, Suzuki T, Li LL, Yang SY. Wu X, et al. Among authors: suzuki t. Bioorg Med Chem Lett. 2016 May 1;26(9):2284-8. doi: 10.1016/j.bmcl.2016.03.048. Epub 2016 Mar 14. Bioorg Med Chem Lett. 2016. PMID: 27020306

2

Novel histone deacetylase inhibitors: design, synthesis, enzyme inhibition, and binding mode study of SAHA-based non-hydroxamates.

Suzuki T, Nagano Y, Matsuura A, Kohara A, Ninomiya S, Kohda K, Miyata N. Suzuki T, et al. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4321-6. doi: 10.1016/j.bmcl.2003.09.048. Bioorg Med Chem Lett. 2003. PMID: 14643318

3

Identification of a potent non-hydroxamate histone deacetylase inhibitor by mechanism-based drug design.

Suzuki T, Matsuura A, Kouketsu A, Nakagawa H, Miyata N. Suzuki T, et al. Bioorg Med Chem Lett. 2005 Jan 17;15(2):331-5. doi: 10.1016/j.bmcl.2004.10.074. Bioorg Med Chem Lett. 2005. PMID: 15603949

4

Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole.

Ishida T, Suzuki T, Hirashima S, Mizutani K, Yoshida A, Ando I, Ikeda S, Adachi T, Hashimoto H. Ishida T, et al. Among authors: suzuki t. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1859-63. doi: 10.1016/j.bmcl.2006.01.032. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16455252

5

Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.

Hirashima S, Suzuki T, Ishida T, Noji S, Yata S, Ando I, Komatsu M, Ikeda S, Hashimoto H. Hirashima S, et al. Among authors: suzuki t. J Med Chem. 2006 Jul 27;49(15):4721-36. doi: 10.1021/jm060269e. J Med Chem. 2006. PMID: 16854079

6

New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation.

Kimata A, Nakagawa H, Ohyama R, Fukuuchi T, Ohta S, Doh-ura K, Suzuki T, Miyata N. Kimata A, et al. Among authors: suzuki t. J Med Chem. 2007 Oct 18;50(21):5053-6. doi: 10.1021/jm070688r. Epub 2007 Sep 13. J Med Chem. 2007. PMID: 17850126

7

Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors.

Itoh Y, Suzuki T, Kouketsu A, Suzuki N, Maeda S, Yoshida M, Nakagawa H, Miyata N. Itoh Y, et al. Among authors: suzuki n, suzuki t. J Med Chem. 2007 Nov 1;50(22):5425-38. doi: 10.1021/jm7009217. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929798

8

Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists.

Suzuki T, Igari S, Hirasawa A, Hata M, Ishiguro M, Fujieda H, Itoh Y, Hirano T, Nakagawa H, Ogura M, Makishima M, Tsujimoto G, Miyata N. Suzuki T, et al. J Med Chem. 2008 Dec 11;51(23):7640-4. doi: 10.1021/jm800970b. J Med Chem. 2008. PMID: 19007110

9

Design, synthesis, inhibitory activity, and binding mode study of novel DNA methyltransferase 1 inhibitors.

Suzuki T, Tanaka R, Hamada S, Nakagawa H, Miyata N. Suzuki T, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1124-7. doi: 10.1016/j.bmcl.2009.12.016. Epub 2009 Dec 21. Bioorg Med Chem Lett. 2010. PMID: 20056538

10

Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

Hamada S, Suzuki T, Mino K, Koseki K, Oehme F, Flamme I, Ozasa H, Itoh Y, Ogasawara D, Komaarashi H, Kato A, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N. Hamada S, et al. Among authors: suzuki t. J Med Chem. 2010 Aug 12;53(15):5629-38. doi: 10.1021/jm1003655. J Med Chem. 2010. PMID: 20684604

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