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Trop-2 Induces Tumor Growth Through AKT and Determines Sensitivity to AKT Inhibitors.
Guerra E, Trerotola M, Tripaldi R, Aloisi AL, Simeone P, Sacchetti A, Relli V, D'Amore A, La Sorda R, Lattanzio R, Piantelli M, Alberti S. Guerra E, et al. Among authors: sacchetti a. Clin Cancer Res. 2016 Aug 15;22(16):4197-205. doi: 10.1158/1078-0432.CCR-15-1701. Epub 2016 Mar 28. Clin Cancer Res. 2016. PMID: 27022065
Human Trop-2 is a tumor-associated calcium signal transducer.
Ripani E, Sacchetti A, Corda D, Alberti S. Ripani E, et al. Among authors: sacchetti a. Int J Cancer. 1998 May 29;76(5):671-6. doi: 10.1002/(sici)1097-0215(19980529)76:5<671::aid-ijc10>3.0.co;2-7. Int J Cancer. 1998. PMID: 9610724
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion.
Guerra E, Relli V, Ceci M, Tripaldi R, Simeone P, Aloisi AL, Pantalone L, La Sorda R, Lattanzio R, Sacchetti A, Havas K, Guarnieri S, Vergara D, Fournier I, Salzet M, Tinari N, Piantelli M, Trerotola M, Alberti S. Guerra E, et al. Among authors: sacchetti a. Oncogene. 2022 Mar;41(12):1795-1808. doi: 10.1038/s41388-022-02220-1. Epub 2022 Feb 7. Oncogene. 2022. PMID: 35132180
The SW480 cell line as a model of resident and migrating colon cancer stem cells.
Verhagen MP, Xu T, Stabile R, Joosten R, Tucci FA, van Royen M, Trerotola M, Alberti S, Sacchetti A, Fodde R. Verhagen MP, et al. Among authors: sacchetti a. iScience. 2024 Aug 5;27(9):110658. doi: 10.1016/j.isci.2024.110658. eCollection 2024 Sep 20. iScience. 2024. PMID: 39246444 Free PMC article.
253 results