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Page 1
Candidalysin is a fungal peptide toxin critical for mucosal infection.
Moyes DL, Wilson D, Richardson JP, Mogavero S, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR. Moyes DL, et al. Among authors: kichik n. Nature. 2016 Apr 7;532(7597):64-8. doi: 10.1038/nature17625. Epub 2016 Mar 30. Nature. 2016. PMID: 27027296 Free PMC article.
Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence.
Richardson JP, Mogavero S, Moyes DL, Blagojevic M, Krüger T, Verma AH, Coleman BM, De La Cruz Diaz J, Schulz D, Ponde NO, Carrano G, Kniemeyer O, Wilson D, Bader O, Enoiu SI, Ho J, Kichik N, Gaffen SL, Hube B, Naglik JR. Richardson JP, et al. Among authors: kichik n. mBio. 2018 Jan 23;9(1):e02178-17. doi: 10.1128/mBio.02178-17. mBio. 2018. PMID: 29362237 Free PMC article.
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor.
Ho J, Yang X, Nikou SA, Kichik N, Donkin A, Ponde NO, Richardson JP, Gratacap RL, Archambault LS, Zwirner CP, Murciano C, Henley-Smith R, Thavaraj S, Tynan CJ, Gaffen SL, Hube B, Wheeler RT, Moyes DL, Naglik JR. Ho J, et al. Among authors: kichik n. Nat Commun. 2019 May 24;10(1):2297. doi: 10.1038/s41467-019-09915-2. Nat Commun. 2019. PMID: 31127085 Free PMC article.
Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins.
Richardson JP, Brown R, Kichik N, Lee S, Priest E, Mogavero S, Maufrais C, Wickramasinghe DN, Tsavou A, Kotowicz NK, Hepworth OW, Gallego-Cortés A, Ponde NO, Ho J, Moyes DL, Wilson D, D'Enfert C, Hube B, Naglik JR. Richardson JP, et al. Among authors: kichik n. mBio. 2022 Feb 22;13(1):e0351021. doi: 10.1128/mbio.03510-21. Epub 2022 Jan 25. mBio. 2022. PMID: 35073742 Free PMC article.
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis.
Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, Zheng H, Richardson JP, Hube B, Naglik JR, Corry DB. Wu Y, et al. Among authors: kichik n. Cell Rep. 2023 Oct 31;42(10):113240. doi: 10.1016/j.celrep.2023.113240. Epub 2023 Oct 17. Cell Rep. 2023. PMID: 37819761 Free PMC article.
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