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Page 1
ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, Knight P, Wang M, Han X, Fryer JD, Fitzgerald ML, Ohyagi Y, Younkin SG, Bu G, Kanekiyo T. Sakae N, et al. Among authors: younkin l, younkin sg. J Neurosci. 2016 Mar 30;36(13):3848-59. doi: 10.1523/JNEUROSCI.3757-15.2016. J Neurosci. 2016. PMID: 27030769 Free PMC article.
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.
Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG. Kawarabayashi T, et al. Among authors: younkin lh, younkin sg. J Neurosci. 2004 Apr 14;24(15):3801-9. doi: 10.1523/JNEUROSCI.5543-03.2004. J Neurosci. 2004. PMID: 15084661 Free PMC article.
BRI2 (ITM2b) inhibits Abeta deposition in vivo.
Kim J, Miller VM, Levites Y, West KJ, Zwizinski CW, Moore BD, Troendle FJ, Bann M, Verbeeck C, Price RW, Smithson L, Sonoda L, Wagg K, Rangachari V, Zou F, Younkin SG, Graff-Radford N, Dickson D, Rosenberry T, Golde TE. Kim J, et al. Among authors: younkin sg. J Neurosci. 2008 Jun 4;28(23):6030-6. doi: 10.1523/JNEUROSCI.0891-08.2008. J Neurosci. 2008. PMID: 18524908 Free PMC article.
Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.
Carrasquillo MM, Belbin O, Zou F, Allen M, Ertekin-Taner N, Ansari M, Wilcox SL, Kashino MR, Ma L, Younkin LH, Younkin SG, Younkin CS, Dincman TA, Howard ME, Howell CC, Stanton CM, Watson CM, Crump M, Vitart V, Hayward C, Hastie ND, Rudan I, Campbell H, Polasek O, Brown K, Passmore P, Craig D, McGuinness B, Todd S, Kehoe PG, Mann DM, Smith AD, Beaumont H, Warden D, Holmes C, Heun R, Kölsch H, Kalsheker N, Pankratz VS, Dickson DW, Graff-Radford NR, Petersen RC, Wright AF, Younkin SG, Morgan K. Carrasquillo MM, et al. Among authors: younkin lh, younkin cs, younkin sg. PLoS One. 2010 Jan 19;5(1):e8764. doi: 10.1371/journal.pone.0008764. PLoS One. 2010. PMID: 20098734 Free PMC article.
Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease.
Zou F, Carrasquillo MM, Pankratz VS, Belbin O, Morgan K, Allen M, Wilcox SL, Ma L, Walker LP, Kouri N, Burgess JD, Younkin LH, Younkin SG, Younkin CS, Bisceglio GD, Crook JE, Dickson DW, Petersen RC, Graff-Radford N, Younkin SG, Ertekin-Taner N. Zou F, et al. Among authors: younkin lh, younkin cs, younkin sg. Neurology. 2010 Feb 9;74(6):480-6. doi: 10.1212/WNL.0b013e3181d07654. Neurology. 2010. PMID: 20142614 Free PMC article.
LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD).
Lincoln S, Allen M, Cox CL, Walker LP, Malphrus K, Qiu Y, Nguyen T, Rowley C, Kouri N, Crook J, Pankratz VS, Younkin S, Younkin L, Carrasquillo M, Zou F, Abdul-Hay SO, Springer W, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Lewis JM, Dickson D, Graff-Radford NR, Petersen RC, Eckman E, Younkin SG, Ertekin-Taner N. Lincoln S, et al. Among authors: younkin l, younkin sg, younkin s. PLoS One. 2013 Jun 4;8(6):e64164. doi: 10.1371/journal.pone.0064164. Print 2013. PLoS One. 2013. PMID: 23750206 Free PMC article.
275 results