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Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects.
Toyn JH, Boy KM, Raybon J, Meredith JE Jr, Robertson AS, Guss V, Hoque N, Sweeney F, Zhuo X, Clarke W, Snow K, Denton RR, Zuev D, Thompson LA, Morrison J, Grace J, Berisha F, Furlong M, Wang JS, Lentz KA, Padmanabha R, Cook L, Wei C, Drexler DM, Macor JE, Albright CF, Gasior M, Olson RE, Hong Q, Soares HD, AbuTarif M, Ahlijanian MK. Toyn JH, et al. J Pharmacol Exp Ther. 2016 Jul;358(1):125-37. doi: 10.1124/jpet.116.232249. Epub 2016 Apr 20. J Pharmacol Exp Ther. 2016. PMID: 27189974 Free PMC article.
Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.
Toyn JH, Thompson LA, Lentz KA, Meredith JE Jr, Burton CR, Sankaranararyanan S, Guss V, Hall T, Iben LG, Krause CM, Krause R, Lin XA, Pierdomenico M, Polson C, Robertson AS, Denton RR, Grace JE, Morrison J, Raybon J, Zhuo X, Snow K, Padmanabha R, Agler M, Esposito K, Harden D, Prack M, Varma S, Wong V, Zhu Y, Zvyaga T, Gerritz S, Marcin LR, Higgins MA, Shi J, Wei C, Cantone JL, Drexler DM, Macor JE, Olson RE, Ahlijanian MK, Albright CF. Toyn JH, et al. Int J Alzheimers Dis. 2014;2014:431858. doi: 10.1155/2014/431858. Epub 2014 Jul 8. Int J Alzheimers Dis. 2014. PMID: 25097793 Free PMC article.
Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells.
Kulhankova K, Cheng AX, Traore S, Auger M, Pelletier M, Hervault M, Wells KD, Green JA, Byrne A, Nelson B, Sponchiado M, Boosani C, Heffner CS, Snow KJ, Murray SA, Villacreses RA, Rector MV, Gansemer ND, Stoltz DA, Allamargot C, Couture F, Hemez C, Hallée S, Barbeau X, Harvey M, Lauvaux C, Gaillet B, Newby GA, Liu DR, McCray PB Jr, Guay D. Kulhankova K, et al. Among authors: snow kj. Nucleic Acids Res. 2024 Oct 28;52(19):11911-11925. doi: 10.1093/nar/gkae819. Nucleic Acids Res. 2024. PMID: 39315713 Free PMC article.
A Comprehensive Atlas of AAV Tropism in the Mouse.
Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR. Walkey CJ, et al. Among authors: snow kj. bioRxiv [Preprint]. 2024 Sep 10:2024.09.10.612279. doi: 10.1101/2024.09.10.612279. bioRxiv. 2024. PMID: 39314496 Free PMC article. Preprint.
39 results