Vassar R - Search Results

1

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.

Yan R, Fan Q, Zhou J, Vassar R. Yan R, et al. Among authors: vassar r. Neurosci Biobehav Rev. 2016 Jun;65:326-40. doi: 10.1016/j.neubiorev.2016.03.025. Epub 2016 Apr 1. Neurosci Biobehav Rev. 2016. PMID: 27044452 Free PMC article. Review.

2

Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models.

Alia AO, Jeon S, Popovic J, Salvo MA, Sadleir KR, Vassar R, Cuddy LK. Alia AO, et al. Among authors: vassar r. Sci Rep. 2022 Dec 21;12(1):22099. doi: 10.1038/s41598-022-26671-4. Sci Rep. 2022. PMID: 36543864 Free PMC article.

3

The beta-secretase, BACE: a prime drug target for Alzheimer's disease.

Vassar R. Vassar R. J Mol Neurosci. 2001 Oct;17(2):157-70. doi: 10.1385/JMN:17:2:157. J Mol Neurosci. 2001. PMID: 11816789 Review.

4

Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Vassar R. Vassar R. Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602. doi: 10.1016/s0169-409x(02)00157-6. Adv Drug Deliv Rev. 2002. PMID: 12453676 Review.

5

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease.

Ohno M, Sametsky EA, Younkin LH, Oakley H, Younkin SG, Citron M, Vassar R, Disterhoft JF. Ohno M, et al. Among authors: vassar r. Neuron. 2004 Jan 8;41(1):27-33. doi: 10.1016/s0896-6273(03)00810-9. Neuron. 2004. PMID: 14715132 Free article.

6

BACE1: the beta-secretase enzyme in Alzheimer's disease.

Vassar R. Vassar R. J Mol Neurosci. 2004;23(1-2):105-14. doi: 10.1385/JMN:23:1-2:105. J Mol Neurosci. 2004. PMID: 15126696 Review.

7

beta-Secretase, APP and Abeta in Alzheimer's disease.

Vassar R. Vassar R. Subcell Biochem. 2005;38:79-103. Subcell Biochem. 2005. PMID: 15709474 Review.

8

Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.

Velliquette RA, O'Connor T, Vassar R. Velliquette RA, et al. Among authors: vassar r. J Neurosci. 2005 Nov 23;25(47):10874-83. doi: 10.1523/JNEUROSCI.2350-05.2005. J Neurosci. 2005. PMID: 16306400 Free PMC article.

9

Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.

Ohno M, Chang L, Tseng W, Oakley H, Citron M, Klein WL, Vassar R, Disterhoft JF. Ohno M, et al. Among authors: vassar r. Eur J Neurosci. 2006 Jan;23(1):251-60. doi: 10.1111/j.1460-9568.2005.04551.x. Eur J Neurosci. 2006. PMID: 16420434

10

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R. Oakley H, et al. Among authors: vassar r. J Neurosci. 2006 Oct 4;26(40):10129-40. doi: 10.1523/JNEUROSCI.1202-06.2006. J Neurosci. 2006. PMID: 17021169 Free PMC article.

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