Kool J - Search Results

1

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

Otvos RA, van Nierop P, Niessen WM, Kini RM, Somsen GW, Smit AB, Kool J. Otvos RA, et al. Among authors: kool j. Anal Chem. 2016 May 3;88(9):4825-32. doi: 10.1021/acs.analchem.6b00455. Epub 2016 Apr 20. Anal Chem. 2016. PMID: 27046509

2

Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.

Kool J, van Liempd SM, Ramautar R, Schenk T, Meerman JH, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. J Biomol Screen. 2005 Aug;10(5):427-36. doi: 10.1177/1087057105274904. J Biomol Screen. 2005. PMID: 16093552

3

On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.

van Liempd SM, Kool J, Niessen WM, van Elswijk DE, Irth H, Vermeulen NP. van Liempd SM, et al. Among authors: kool j. Drug Metab Dispos. 2006 Sep;34(9):1640-9. doi: 10.1124/dmd.106.010355. Epub 2006 Jun 21. Drug Metab Dispos. 2006. PMID: 16790557

4

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6.

Kool J, van Liempd SM, Harmsen S, Beckman J, van Elswijk D, Commandeur JN, Irth H, Vermeulen NP. Kool J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):49-58. doi: 10.1016/j.jchromb.2007.08.005. Epub 2007 Aug 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17826363

5

Reversed-phase liquid chromatography coupled on-line to estrogen receptor bioaffinity detection based on fluorescence polarization.

Reinen J, Kool J, Vermeulen NP. Reinen J, et al. Among authors: kool j. Anal Bioanal Chem. 2008 Apr;390(8):1987-98. doi: 10.1007/s00216-008-1833-2. Epub 2008 Jan 31. Anal Bioanal Chem. 2008. PMID: 18236033 Free PMC article.

6

Development of a countergradient parking system for gradient liquid chromatography with online biochemical detection of serine protease inhibitors.

Schebb NH, Heus F, Saenger T, Karst U, Irth H, Kool J. Schebb NH, et al. Among authors: kool j. Anal Chem. 2008 Sep 1;80(17):6764-72. doi: 10.1021/ac801035e. Epub 2008 Aug 8. Anal Chem. 2008. PMID: 18686973

7

Online screening of homogeneous catalyst performance using reaction detection mass spectrometry.

Martha CT, Elders N, Krabbe JG, Kool J, Niessen WM, Orru RV, Irth H. Martha CT, et al. Among authors: kool j. Anal Chem. 2008 Sep 15;80(18):7121-7. doi: 10.1021/ac801003h. Epub 2008 Aug 13. Anal Chem. 2008. PMID: 18698801

8

Screening of protein-ligand interactions using dynamic protein-affinity chromatography solid-phase extraction-liquid chromatography-mass spectrometry.

Jonker N, Kool J, Krabbe JG, Retra K, Lingeman H, Irth H. Jonker N, et al. Among authors: kool j. J Chromatogr A. 2008 Sep 26;1205(1-2):71-7. doi: 10.1016/j.chroma.2008.07.089. Epub 2008 Aug 7. J Chromatogr A. 2008. PMID: 18715568

9

Analysis of glutathione adducts of patulin by means of liquid chromatography (HPLC) with biochemical detection (BCD) and electrospray ionization tandem mass spectrometry (ESI-MS/MS).

Schebb NH, Faber H, Maul R, Heus F, Kool J, Irth H, Karst U. Schebb NH, et al. Among authors: kool j. Anal Bioanal Chem. 2009 Jul;394(5):1361-73. doi: 10.1007/s00216-009-2765-1. Epub 2009 Apr 24. Anal Bioanal Chem. 2009. PMID: 19390846

10

Online magnetic bead dynamic protein-affinity selection coupled to LC-MS for the screening of pharmacologically active compounds.

Jonker N, Kretschmer A, Kool J, Fernandez A, Kloos D, Krabbe JG, Lingeman H, Irth H. Jonker N, et al. Among authors: kool j. Anal Chem. 2009 Jun 1;81(11):4263-70. doi: 10.1021/ac9000755. Anal Chem. 2009. PMID: 19476387

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