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CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism.
Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. Dorr CR, et al. Among authors: muthusamy a. Drug Metab Dispos. 2017 Aug;45(8):957-965. doi: 10.1124/dmd.117.076307. Epub 2017 May 22. Drug Metab Dispos. 2017. PMID: 28533324 Free PMC article.
Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing.
Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK; for DeKAF Genomics. Dorr CR, et al. Among authors: muthusamy a. Pharmacogenomics J. 2019 Aug;19(4):375-389. doi: 10.1038/s41397-018-0063-z. Epub 2018 Nov 16. Pharmacogenomics J. 2019. PMID: 30442921 Free PMC article.
Extreme Phenotype Sampling and Next Generation Sequencing to Identify Genetic Variants Associated with Tacrolimus in African American Kidney Transplant Recipients.
Mohamed M, Guo B, Wu B, Schladt D, Muthusamy A, Guan W, Abrahante J, Onyeaghala G, Saqr A, Pankratz N, Agarwal G, Mannon R, Matas A, Oetting W, Remmel R, Israni A, Jacobson P, Dorr C. Mohamed M, et al. Among authors: muthusamy a. Res Sq [Preprint]. 2024 Mar 14:rs.3.rs-4050136. doi: 10.21203/rs.3.rs-4050136/v1. Res Sq. 2024. Update in: Pharmacogenomics J. 2024 Aug 23;24(5):29. doi: 10.1038/s41397-024-00349-8 PMID: 38558983 Free PMC article. Updated. Preprint.
Extreme phenotype sampling and next generation sequencing to identify genetic variants associated with tacrolimus in African American kidney transplant recipients.
Mohamed ME, Guo B, Wu B, Schladt DP, Muthusamy A, Guan W, Abrahante JE, Onyeaghala G, Saqr A, Pankratz N, Agarwal G, Mannon RB, Matas AJ, Oetting WS, Remmel RP, Israni AK, Jacobson PA; DeKAF Genomics and GEN03 Investigators; Dorr CR. Mohamed ME, et al. Among authors: muthusamy a. Pharmacogenomics J. 2024 Aug 23;24(5):29. doi: 10.1038/s41397-024-00349-8. Pharmacogenomics J. 2024. PMID: 39179559
Development of a Uniform Apheresis Case Report Form for Standardized Collection of Apheresis Data.
Johnson AD, Szczepiorkowski ZM, Balogun RA, Karam O, Nellis M, Schneiderman J, Schwartz J, Winters JL, Wu Y, Armendariz T, Burgstaler E, Collins L, Geile K, Pavenski K, Sanchez AP, Witt V, Muthusamy A, Pederson T, Ramesh V, Thao M, Chlebeck T, Zantek ND. Johnson AD, et al. Among authors: muthusamy a. J Clin Apher. 2024 Oct;39(5):e22146. doi: 10.1002/jca.22146. J Clin Apher. 2024. PMID: 39420527
127 results