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Page 1
Dominant mutations of the Notch ligand Jagged1 cause peripheral neuropathy.
Sullivan JM, Motley WW, Johnson JO, Aisenberg WH, Marshall KL, Barwick KE, Kong L, Huh JS, Saavedra-Rivera PC, McEntagart MM, Marion MH, Hicklin LA, Modarres H, Baple EL, Farah MH, Zuberi AR, Lutz CM, Gaudet R, Traynor BJ, Crosby AH, Sumner CJ. Sullivan JM, et al. Among authors: aisenberg wh. J Clin Invest. 2020 Mar 2;130(3):1506-1512. doi: 10.1172/JCI128152. J Clin Invest. 2020. PMID: 32065591 Free PMC article.
TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2.
Woolums BM, McCray BA, Sung H, Tabuchi M, Sullivan JM, Ruppell KT, Yang Y, Mamah C, Aisenberg WH, Saavedra-Rivera PC, Larin BS, Lau AR, Robinson DN, Xiang Y, Wu MN, Sumner CJ, Lloyd TE. Woolums BM, et al. Among authors: aisenberg wh. Nat Commun. 2020 May 29;11(1):2679. doi: 10.1038/s41467-020-16411-5. Nat Commun. 2020. PMID: 32471994 Free PMC article.
Identification and characterization of novel renal sensory receptors.
Rajkumar P, Aisenberg WH, Acres OW, Protzko RJ, Pluznick JL. Rajkumar P, et al. Among authors: aisenberg wh. PLoS One. 2014 Oct 23;9(10):e111053. doi: 10.1371/journal.pone.0111053. eCollection 2014. PLoS One. 2014. PMID: 25340336 Free PMC article.
Defining an olfactory receptor function in airway smooth muscle cells.
Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, Pluznick JL, An SS. Aisenberg WH, et al. Sci Rep. 2016 Dec 1;6:38231. doi: 10.1038/srep38231. Sci Rep. 2016. PMID: 27905542 Free PMC article.
Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses.
Aisenberg LK, Rousseau KE, Cascino K, Massaccesi G, Aisenberg WH, Luo W, Muthumani K, Weiner DB, Whitehead SS, Chattergoon MA, Durbin AP, Cox AL. Aisenberg LK, et al. Among authors: aisenberg wh. JCI Insight. 2022 Jun 22;7(12):e151782. doi: 10.1172/jci.insight.151782. JCI Insight. 2022. PMID: 35588060 Free PMC article.
Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology.
Nemec KM, Uy G, Chaluvadi VS, Purnell FS, Elfayoumi B, O'Brien CA, Aisenberg WH, Lombroso SI, Guo X, Blank N, Oon CH, Yaqoob F, Temsamrit B, Rawat P, Thaiss CA, Wang Q, Bennett ML, Bennett FC. Nemec KM, et al. Among authors: aisenberg wh. bioRxiv [Preprint]. 2024 Sep 20:2024.09.18.613629. doi: 10.1101/2024.09.18.613629. bioRxiv. 2024. PMID: 39345609 Free PMC article. Preprint.
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice.
Sullivan JM, Bagnell AM, Alevy J, Avila EM, Mihaljević L, Saavedra-Rivera PC, Kong L, Huh JS, McCray BA, Aisenberg WH, Zuberi AR, Bogdanik L, Lutz CM, Qiu Z, Quinlan KA, Searson PC, Sumner CJ. Sullivan JM, et al. Among authors: aisenberg wh. Sci Transl Med. 2024 May 22;16(748):eadk1358. doi: 10.1126/scitranslmed.adk1358. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776392 Free PMC article.
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