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Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
Novakova Z, Wozniak K, Jancarik A, Rais R, Wu Y, Pavlicek J, Ferraris D, Havlinova B, Ptacek J, Vavra J, Hin N, Rojas C, Majer P, Slusher BS, Tsukamoto T, Barinka C. Novakova Z, et al. Among authors: jancarik a. J Med Chem. 2016 May 26;59(10):4539-50. doi: 10.1021/acs.jmedchem.5b01806. Epub 2016 Apr 25. J Med Chem. 2016. PMID: 27074627
Tuning the Diradical Character of Pentacene Derivatives via Non-Benzenoid Coupling Motifs.
Wang T, Angulo-Portugal P, Berdonces-Layunta A, Jancarik A, Gourdon A, Holec J, Kumar M, Soler D, Jelinek P, Casanova D, Corso M, de Oteyza DG, Calupitan JP. Wang T, et al. Among authors: jancarik a. J Am Chem Soc. 2023 May 10;145(18):10333-10341. doi: 10.1021/jacs.3c02027. Epub 2023 Apr 26. J Am Chem Soc. 2023. PMID: 37099608 Free PMC article.
Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
Rais R, Jančařík A, Tenora L, Nedelcovych M, Alt J, Englert J, Rojas C, Le A, Elgogary A, Tan J, Monincová L, Pate K, Adams R, Ferraris D, Powell J, Majer P, Slusher BS. Rais R, et al. Among authors: jancarik a. J Med Chem. 2016 Sep 22;59(18):8621-33. doi: 10.1021/acs.jmedchem.6b01069. Epub 2016 Sep 6. J Med Chem. 2016. PMID: 27560860
N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders.
Nedelcovych MT, Tenora L, Kim BH, Kelschenbach J, Chao W, Hadas E, Jančařík A, Prchalová E, Zimmermann SC, Dash RP, Gadiano AJ, Garrett C, Furtmüller G, Oh B, Brandacher G, Alt J, Majer P, Volsky DJ, Rais R, Slusher BS. Nedelcovych MT, et al. Among authors: jancarik a. J Med Chem. 2017 Aug 24;60(16):7186-7198. doi: 10.1021/acs.jmedchem.7b00966. Epub 2017 Aug 14. J Med Chem. 2017. PMID: 28759224 Free PMC article.
41 results