Clapham B - Search Results

1

Synthesis and Pharmacology of (Pyridin-2-yl)methanol Derivatives as Novel and Selective Transient Receptor Potential Vanilloid 3 Antagonists.

Gomtsyan A, Schmidt RG, Bayburt EK, Gfesser GA, Voight EA, Daanen JF, Schmidt DL, Cowart MD, Liu H, Altenbach RJ, Kort ME, Clapham B, Cox PB, Shrestha A, Henry R, Whittern DN, Reilly RM, Puttfarcken PS, Brederson JD, Song P, Li B, Huang SM, McDonald HA, Neelands TR, McGaraughty SP, Gauvin DM, Joshi SK, Banfor PN, Segreti JA, Shebley M, Faltynek CR, Dart MJ, Kym PR. Gomtsyan A, et al. Among authors: clapham b. J Med Chem. 2016 May 26;59(10):4926-47. doi: 10.1021/acs.jmedchem.6b00287. Epub 2016 May 2. J Med Chem. 2016. PMID: 27077528

2

Synthesis and optimization of furano[3,2-d]pyrimidines as selective spleen tyrosine kinase (Syk) inhibitors.

Hoemann M, Wilson N, Argiriadi M, Banach D, Burchat A, Calderwood D, Clapham B, Cox P, Duignan DB, Konopacki D, Somal G, Vasudevan A. Hoemann M, et al. Among authors: clapham b. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5562-5567. doi: 10.1016/j.bmcl.2016.09.077. Epub 2016 Oct 11. Bioorg Med Chem Lett. 2016. PMID: 27789138

3

N-H insertion reactions of primary ureas: the synthesis of highly substituted imidazolones and imidazoles from diazocarbonyls.

Lee SH, Yoshida K, Matsushita H, Clapham B, Koch G, Zimmermann J, Janda KD. Lee SH, et al. Among authors: clapham b. J Org Chem. 2004 Dec 10;69(25):8829-35. doi: 10.1021/jo048353u. J Org Chem. 2004. PMID: 15575764

4

Preparation of soluble and insoluble polymer supported IBX reagents.

Reed NN, Delgado M, Hereford K, Clapham B, Janda KD. Reed NN, et al. Among authors: clapham b. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2047-9. doi: 10.1016/s0960-894x(02)00264-0. Bioorg Med Chem Lett. 2002. PMID: 12113839

5

Construction and validation of an automated flow hydrogenation instrument for application in high-throughput organic chemistry.

Clapham B, Wilson NS, Michmerhuizen MJ, Blanchard DP, Dingle DM, Nemcek TA, Pan JY, Sauer DR. Clapham B, et al. J Comb Chem. 2008 Jan-Feb;10(1):88-93. doi: 10.1021/cc700178a. Epub 2007 Dec 21. J Comb Chem. 2008. PMID: 18095655

6

Preparation of new microgel polymers and their application as supports in organic synthesis.

Spanka C, Clapham B, Janda KD. Spanka C, et al. Among authors: clapham b. J Org Chem. 2002 May 3;67(9):3045-50. doi: 10.1021/jo016362m. J Org Chem. 2002. PMID: 11975565

7

Rhodium carbenoid N-H insertion reactions of primary ureas: solution and solid-phase synthesis of imidazolones.

Lee SH, Clapham B, Koch G, Zimmermann J, Janda KD. Lee SH, et al. Among authors: clapham b. Org Lett. 2003 Feb 20;5(4):511-4. doi: 10.1021/ol020244j. Org Lett. 2003. PMID: 12583756

8

Solid-phase rhodium carbenoid N-H insertion reactions: the synthesis of a diverse array of indoles.

Lee SH, Clapham B, Koch G, Zimmermann J, Janda KD. Lee SH, et al. Among authors: clapham b. J Comb Chem. 2003 Mar-Apr;5(2):188-96. doi: 10.1021/cc020079z. J Comb Chem. 2003. PMID: 12625710

9

Suspension ring-opening metathesis polymerization: the preparation of norbornene-based resins for application in organic synthesis.

Lee BS, Mahajan S, Clapham B, Janda KD. Lee BS, et al. Among authors: clapham b. J Org Chem. 2004 May 14;69(10):3319-29. doi: 10.1021/jo049827s. J Org Chem. 2004. PMID: 15132537

10

Smart cleavage reactions: the synthesis of an array of ureas from polymer-bound carbamates.

Lee SH, Matsushita H, Koch G, Zimmermann J, Clapham B, Janda KD. Lee SH, et al. Among authors: clapham b. J Comb Chem. 2004 Sep-Oct;6(5):822-7. doi: 10.1021/cc049916i. J Comb Chem. 2004. PMID: 15360219

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