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Page 1
Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array.
Fuller CW, Kumar S, Porel M, Chien M, Bibillo A, Stranges PB, Dorwart M, Tao C, Li Z, Guo W, Shi S, Korenblum D, Trans A, Aguirre A, Liu E, Harada ET, Pollard J, Bhat A, Cech C, Yang A, Arnold C, Palla M, Hovis J, Chen R, Morozova I, Kalachikov S, Russo JJ, Kasianowicz JJ, Davis R, Roever S, Church GM, Ju J. Fuller CW, et al. Among authors: roever s. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5233-8. doi: 10.1073/pnas.1601782113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091962 Free PMC article.
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array.
Stranges PB, Palla M, Kalachikov S, Nivala J, Dorwart M, Trans A, Kumar S, Porel M, Chien M, Tao C, Morozova I, Li Z, Shi S, Aberra A, Arnold C, Yang A, Aguirre A, Harada ET, Korenblum D, Pollard J, Bhat A, Gremyachinskiy D, Bibillo A, Chen R, Davis R, Russo JJ, Fuller CW, Roever S, Ju J, Church GM. Stranges PB, et al. Among authors: roever s. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6749-E6756. doi: 10.1073/pnas.1608271113. Epub 2016 Oct 11. Proc Natl Acad Sci U S A. 2016. PMID: 27729524 Free PMC article.
Multiplex Single-Molecule Kinetics of Nanopore-Coupled Polymerases.
Palla M, Punthambaker S, Stranges B, Vigneault F, Nivala J, Wiegand D, Ayer A, Craig T, Gremyachinskiy D, Franklin H, Sun S, Pollard J, Trans A, Arnold C, Schwab C, Mcgaw C, Sarvabhowman P, Dalal D, Thai E, Amato E, Lederman I, Taing M, Kelley S, Qwan A, Fuller CW, Roever S, Church GM. Palla M, et al. Among authors: roever s. ACS Nano. 2021 Jan 26;15(1):489-502. doi: 10.1021/acsnano.0c05226. Epub 2020 Dec 28. ACS Nano. 2021. PMID: 33370106
Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Wright MB, Varona Santos J, Kemmer C, Maugeais C, Carralot JP, Roever S, Molina J, Ducasa GM, Mitrofanova A, Sloan A, Ahmad A, Pedigo C, Ge M, Pressly J, Barisoni L, Mendez A, Sgrignani J, Cavalli A, Merscher S, Prunotto M, Fornoni A. Wright MB, et al. Among authors: roever s. Nat Commun. 2021 Aug 2;12(1):4662. doi: 10.1038/s41467-021-24890-3. Nat Commun. 2021. PMID: 34341345 Free PMC article.
Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.
Richter HG, Adams DR, Benardeau A, Bickerdike MJ, Bentley JM, Blench TJ, Cliffe IA, Dourish C, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Monck NJ, Plancher JM, Roever S, Roffey JR, Taylor S, Vickers SP. Richter HG, et al. Among authors: roever s. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1207-11. doi: 10.1016/j.bmcl.2005.11.083. Epub 2005 Dec 19. Bioorg Med Chem Lett. 2006. PMID: 16361098
Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist.
Gill R, Alanine A, Bourson A, Buttelmann B, Fischer G, Heitz MP, Kew JN, Levet-Trafit B, Lorez HP, Malherbe P, Miss MT, Mutel V, Pinard E, Roever S, Schmitt M, Trube G, Wybrecht R, Wyler R, Kemp JA. Gill R, et al. Among authors: roever s. J Pharmacol Exp Ther. 2002 Sep;302(3):940-8. doi: 10.1124/jpet.102.034322. J Pharmacol Exp Ther. 2002. PMID: 12183650