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209 results

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Page 1
Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.
Mutyam V, Du M, Xue X, Keeling KM, White EL, Bostwick JR, Rasmussen L, Liu B, Mazur M, Hong JS, Falk Libby E, Liang F, Shang H, Mense M, Suto MJ, Bedwell DM, Rowe SM. Mutyam V, et al. Among authors: white el. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1092-1103. doi: 10.1164/rccm.201601-0154OC. Am J Respir Crit Care Med. 2016. PMID: 27104944 Free PMC article.
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Chung WJ, Goeckeler-Fried JL, Havasi V, Chiang A, Rowe SM, Plyler ZE, Hong JS, Mazur M, Piazza GA, Keeton AB, White EL, Rasmussen L, Weissman AM, Denny RA, Brodsky JL, Sorscher EJ. Chung WJ, et al. Among authors: white el. PLoS One. 2016 Oct 12;11(10):e0163615. doi: 10.1371/journal.pone.0163615. eCollection 2016. PLoS One. 2016. PMID: 27732613 Free PMC article.
AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease.
Cochran JN, Diggs PV, Nebane NM, Rasmussen L, White EL, Bostwick R, Maddry JA, Suto MJ, Roberson ED. Cochran JN, et al. Among authors: white el. J Biomol Screen. 2014 Dec;19(10):1338-49. doi: 10.1177/1087057114547232. Epub 2014 Aug 25. J Biomol Screen. 2014. PMID: 25156556 Free PMC article.
A high-throughput screening strategy to overcome virus instability.
Rasmussen L, Maddox C, Moore BP, Severson W, White EL. Rasmussen L, et al. Among authors: white el. Assay Drug Dev Technol. 2011 Apr;9(2):184-90. doi: 10.1089/adt.2010.0298. Epub 2010 Nov 4. Assay Drug Dev Technol. 2011. PMID: 21050067 Free PMC article.
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y. Zhang W, et al. Among authors: white el. Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4. Biochem J. 2016. PMID: 26846349 Free PMC article.
209 results