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Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior.
Wang YJ, Tao YM, Li FY, Wang YH, Xu XJ, Chen J, Cao YL, Chi ZQ, Neumeyer JL, Zhang A, Liu JG. Wang YJ, et al. Among authors: wang yh. J Pharmacol Exp Ther. 2009 Apr;329(1):306-13. doi: 10.1124/jpet.108.142802. Epub 2009 Jan 9. J Pharmacol Exp Ther. 2009. PMID: 19136637 Free PMC article.
Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with κ agonist and μ agonist/antagonist activity.
Sun JF, Wang YH, Chai JR, Li FY, Hang A, Lu G, Tao YM, Cheng Y, Chi ZQ, Neumeyer JL, Zhang A, Liu JG, Wang YJ. Sun JF, et al. Among authors: wang yh, wang yj. Eur J Pharmacol. 2014 Oct 5;740:455-63. doi: 10.1016/j.ejphar.2014.06.045. Epub 2014 Jul 3. Eur J Pharmacol. 2014. PMID: 24998879
Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists.
Gan ZJ, Wang YH, Xu YG, Guo T, Wang J, Song Q, Xu XJ, Hu SY, Wang YJ, Wang DC, Sun DZ, Zhang D, Xi T, Li HD, Zhang HB, Hang TJ, Lu HG, Liu JG. Gan ZJ, et al. Among authors: wang yh, wang dc, wang j, wang yj. Org Biomol Chem. 2015 May 28;13(20):5656-73. doi: 10.1039/c5ob00350d. Epub 2015 Apr 21. Org Biomol Chem. 2015. PMID: 25895552
The role of the dynorphin/κ opioid receptor system in anxiety.
Hang A, Wang YJ, He L, Liu JG. Hang A, et al. Among authors: wang yj. Acta Pharmacol Sin. 2015 Jul;36(7):783-90. doi: 10.1038/aps.2015.32. Epub 2015 May 18. Acta Pharmacol Sin. 2015. PMID: 25982631 Free PMC article. Review.
4,668 results