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A nationwide epidemiological survey of alpha1-antitrypsin deficiency in Japan.
Seyama K, Hirai T, Mishima M, Tatsumi K, Nishimura M; Respiratory Failure Research Group of the Japanese Ministry of Health, Labour, and Welfare. Seyama K, et al. Respir Investig. 2016 May;54(3):201-6. doi: 10.1016/j.resinv.2015.12.002. Epub 2016 Jan 19. Respir Investig. 2016. PMID: 27108016
[Alpha 1-antitrypsin genes in patients with alpha 1AT deficiency in Japan: mutational analysis and allelic background].
Nukiwa T, Seyama K, Takahashi H, Kira S. Nukiwa T, et al. Among authors: seyama k. Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Aug;30(8):1420-6. Nihon Kyobu Shikkan Gakkai Zasshi. 1992. PMID: 1434214 Japanese.
A new alpha 1AT deficient variant, Siiyama (Ser53(TCC)-Phe53(TTC)), was found in a 39-year-old male with pulmonary emphysema (Seyama K, et al, J Biol Chem, 266, 12627, 1991). Interestingly, 6 out of 10 families with alpha 1AT deficiency in Japan shared the identical …
A new alpha 1AT deficient variant, Siiyama (Ser53(TCC)-Phe53(TTC)), was found in a 39-year-old male with pulmonary emphysema (Seyama …
Alpha 1-antitrypsin-deficient variant Siiyama (Ser53[TCC] to Phe53[TTC]) is prevalent in Japan. Status of alpha 1-antitrypsin deficiency in Japan.
Seyama K, Nukiwa T, Souma S, Shimizu K, Kira S. Seyama K, et al. Am J Respir Crit Care Med. 1995 Dec;152(6 Pt 1):2119-26. doi: 10.1164/ajrccm.152.6.8520784. Am J Respir Crit Care Med. 1995. PMID: 8520784
The amino acid substitution in this variant occurs in a highly conserved residue of the serpin (serine protease inhibitor) backbone (Seyama K, et al. 1991. J. Biol. Chem. 266:12627-12632). We attempted to determine whether alpha 1-AT deficiency in Japan was caused b …
The amino acid substitution in this variant occurs in a highly conserved residue of the serpin (serine protease inhibitor) backbone (Seya …
Matrix metalloproteinases in blood from patients with LAM.
Odajima N, Betsuyaku T, Nasuhara Y, Inoue H, Seyama K, Nishimura M. Odajima N, et al. Among authors: seyama k. Respir Med. 2009 Jan;103(1):124-9. doi: 10.1016/j.rmed.2008.07.017. Epub 2008 Aug 29. Respir Med. 2009. PMID: 18760908 Free article.
Additive effects of transdermal tulobuterol to inhaled tiotropium in patients with COPD.
Ichinose M, Seyama K, Nishimura M, Fukuchi Y, Nagai A, Mishima M, Kubo K; Beta-2 Agonist Research and Evaluation Committee in COPD (BAREC) Study Group. Ichinose M, et al. Among authors: seyama k. Respir Med. 2010 Feb;104(2):267-74. doi: 10.1016/j.rmed.2009.09.012. Epub 2009 Oct 28. Respir Med. 2010. PMID: 19875277 Free article. Clinical Trial.
208 results