Fung SY - Search Results

1

Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation.

Rozmus J, McDonald R, Fung SY, Del Bel KL, Roden J, Senger C, Schultz KR, McKinnon ML, Davis J, Turvey SE. Rozmus J, et al. Among authors: fung sy. Clin Immunol. 2016 Jul;168:1-5. doi: 10.1016/j.clim.2016.04.011. Epub 2016 Apr 22. Clin Immunol. 2016. PMID: 27109639

2

Germline CBM-opathies: From immunodeficiency to atopy.

Lu HY, Biggs CM, Blanchard-Rohner G, Fung SY, Sharma M, Turvey SE. Lu HY, et al. Among authors: fung sy. J Allergy Clin Immunol. 2019 May;143(5):1661-1673. doi: 10.1016/j.jaci.2019.03.009. J Allergy Clin Immunol. 2019. PMID: 31060714 Review.

3

Combined immunodeficiency associated with homozygous MALT1 mutations.

McKinnon ML, Rozmus J, Fung SY, Hirschfeld AF, Del Bel KL, Thomas L, Marr N, Martin SD, Marwaha AK, Priatel JJ, Tan R, Senger C, Tsang A, Prendiville J, Junker AK, Seear M, Schultz KR, Sly LM, Holt RA, Patel MS, Friedman JM, Turvey SE. McKinnon ML, et al. Among authors: fung sy. J Allergy Clin Immunol. 2014 May;133(5):1458-62, 1462.e1-7. doi: 10.1016/j.jaci.2013.10.045. Epub 2013 Dec 12. J Allergy Clin Immunol. 2014. PMID: 24332264 Clinical Trial. No abstract available.

4

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.

Turvey SE, Durandy A, Fischer A, Fung SY, Geha RS, Gewies A, Giese T, Greil J, Keller B, McKinnon ML, Neven B, Rozmus J, Ruland J, Snow AL, Stepensky P, Warnatz K. Turvey SE, et al. Among authors: fung sy. J Allergy Clin Immunol. 2014 Aug;134(2):276-84. doi: 10.1016/j.jaci.2014.06.015. J Allergy Clin Immunol. 2014. PMID: 25087226 Free PMC article. Review.

5

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient.

Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, Hersperger R, Turvey SE, Eder J, Bornancin F, Overall CM. Quancard J, et al. Among authors: fung sy. Nat Chem Biol. 2019 Mar;15(3):304-313. doi: 10.1038/s41589-018-0222-1. Epub 2019 Jan 28. Nat Chem Biol. 2019. PMID: 30692685

6

MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness.

Fung SY, Lu HY, Sharma M, Sharma AA, Saferali A, Jia A, Abraham L, Klein T, Gold MR, Noterangelo LD, Overall CM, Turvey SE. Fung SY, et al. Front Immunol. 2021 Oct 14;12:749794. doi: 10.3389/fimmu.2021.749794. eCollection 2021. Front Immunol. 2021. PMID: 34721419 Free PMC article.

7

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.

Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, Overall CM. Klein T, et al. Among authors: fung sy. Nat Commun. 2015 Nov 3;6:8777. doi: 10.1038/ncomms9777. Nat Commun. 2015. PMID: 26525107 Free PMC article.

8

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling.

Yang H, Fung SY, Bao A, Li Q, Turvey SE. Yang H, et al. Among authors: fung sy. J Vis Exp. 2017 Jul 26;(125):56075. doi: 10.3791/56075. J Vis Exp. 2017. PMID: 28784964 Free PMC article.

9

Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production.

Tang AC, Rahavi SM, Fung SY, Lu HY, Yang H, Lim CJ, Reid GS, Turvey SE. Tang AC, et al. Among authors: fung sy. Cell Death Dis. 2018 Feb 7;9(2):162. doi: 10.1038/s41419-017-0194-1. Cell Death Dis. 2018. PMID: 29415982 Free PMC article.

10

Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells.

Yang H, Kozicky L, Saferali A, Fung SY, Afacan N, Cai B, Falsafi R, Gill E, Liu M, Kollmann TR, Hancock RE, Sly LM, Turvey SE. Yang H, et al. Among authors: fung sy. Biomaterials. 2016 Dec;111:90-102. doi: 10.1016/j.biomaterials.2016.09.032. Epub 2016 Oct 3. Biomaterials. 2016. PMID: 27728817

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