Vermeulen A - Search Results

1

PK/PD Modelling of the QT Interval: a Step Towards Defining the Translational Relationship Between In Vitro, Awake Beagle Dogs, and Humans.

Marostica E, Van Ammel K, Teisman A, Gallacher D, Van Bocxlaer J, De Ridder F, Boussery K, Vermeulen A. Marostica E, et al. Among authors: vermeulen a. AAPS J. 2016 Jul;18(4):1000-12. doi: 10.1208/s12248-016-9920-3. Epub 2016 Apr 26. AAPS J. 2016. PMID: 27116025

2

Identifying the translational gap in the evaluation of drug-induced QTc interval prolongation.

Chain AS, Dubois VF, Danhof M, Sturkenboom MC, Della Pasqua O; Cardiovascular Safety Project Team, TI Pharma PKPD Platform. Chain AS, et al. Br J Clin Pharmacol. 2013 Nov;76(5):708-24. doi: 10.1111/bcp.12082. Br J Clin Pharmacol. 2013. PMID: 23351036 Free PMC article. Clinical Trial.

3

Sensitivity of individual items of the Positive and Negative Syndrome Scale (PANSS) and items subgroups to differentiate between placebo and drug treatment in schizophrenia.

Kozielska M, Pilla Reddy V, Johnson M, de Ridder F, Vermeulen A, Liu J, Groothuis GM, Danhof M, Proost JH. Kozielska M, et al. Among authors: vermeulen a. Schizophr Res. 2013 May;146(1-3):53-8. doi: 10.1016/j.schres.2013.01.022. Epub 2013 Feb 20. Schizophr Res. 2013. PMID: 23434198

4

Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data are not on the boundaries.

Xu XS, Samtani MN, Dunne A, Nandy P, Vermeulen A, De Ridder F; Alzheimer’s Disease Neuroimaging Initiative. Xu XS, et al. Among authors: vermeulen a. J Pharmacokinet Pharmacodyn. 2013 Aug;40(4):537-44. doi: 10.1007/s10928-013-9318-0. Epub 2013 May 5. J Pharmacokinet Pharmacodyn. 2013. PMID: 23645382

5

A model based analysis of IPEC dosing of paclitaxel in rats.

Colin P, De Smet L, Vervaet C, Remon JP, Ceelen W, Van Bocxlaer J, Boussery K, Vermeulen A. Colin P, et al. Among authors: vermeulen a. Pharm Res. 2014 Oct;31(10):2876-86. doi: 10.1007/s11095-014-1384-5. Epub 2014 May 22. Pharm Res. 2014. PMID: 24848338

6

Physiology-based IVIVE predictions of tramadol from in vitro metabolism data.

T'jollyn H, Snoeys J, Colin P, Van Bocxlaer J, Annaert P, Cuyckens F, Vermeulen A, Van Peer A, Allegaert K, Mannens G, Boussery K. T'jollyn H, et al. Among authors: vermeulen a. Pharm Res. 2015 Jan;32(1):260-74. doi: 10.1007/s11095-014-1460-x. Epub 2014 Jul 22. Pharm Res. 2015. PMID: 25048637

7

vRNA structured population model for Hepatitis C Virus dynamics.

Woot de Trixhe X, Krzyzanski W, De Ridder F, Vermeulen A. Woot de Trixhe X, et al. Among authors: vermeulen a. J Theor Biol. 2015 Aug 7;378:1-11. doi: 10.1016/j.jtbi.2015.04.017. Epub 2015 Apr 23. J Theor Biol. 2015. PMID: 25912382

8

Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.

T'jollyn H, Snoeys J, Vermeulen A, Michelet R, Cuyckens F, Mannens G, Van Peer A, Annaert P, Allegaert K, Van Bocxlaer J, Boussery K. T'jollyn H, et al. Among authors: vermeulen a. AAPS J. 2015 Nov;17(6):1376-87. doi: 10.1208/s12248-015-9803-z. Epub 2015 Jul 25. AAPS J. 2015. PMID: 26209290 Free PMC article.

9

Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities.

Marostica E, Van Ammel K, Teisman A, Boussery K, Van Bocxlaer J, De Ridder F, Gallacher D, Vermeulen A. Marostica E, et al. Among authors: vermeulen a. J Pharmacokinet Pharmacodyn. 2015 Dec;42(6):659-79. doi: 10.1007/s10928-015-9434-0. Epub 2015 Aug 11. J Pharmacokinet Pharmacodyn. 2015. PMID: 26259721

10

Effects of Food and Pharmaceutical Formulation on Desmopressin Pharmacokinetics in Children.

Michelet R, Dossche L, De Bruyne P, Colin P, Boussery K, Vande Walle J, Van Bocxlaer J, Vermeulen A. Michelet R, et al. Among authors: vermeulen a. Clin Pharmacokinet. 2016 Sep;55(9):1159-70. doi: 10.1007/s40262-016-0393-4. Clin Pharmacokinet. 2016. PMID: 27106176 Clinical Trial.

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