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AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming.
Zhang P, Song Y, Sun Y, Li X, Chen L, Yang L, Xing Y. Zhang P, et al. Among authors: chen l. FASEB J. 2018 Jul;32(7):3924-3935. doi: 10.1096/fj.201701078R. Epub 2018 Mar 5. FASEB J. 2018. PMID: 29505302
Our findings establish that AMPK/GSK3beta/beta-catenin cascade-triggered CEMIP overexpression might promote migration and invasion in anoikis-resistant PCa cells by enhancing PDK4-associated metabolic reprogramming, which may provide a novel, promising therapeutic target for the …
Our findings establish that AMPK/GSK3beta/beta-catenin cascade-triggered CEMIP overexpression might promote migration and invasion in anoiki …
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