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In the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responses.
Audia JP, Lindsey AS, Housley NA, Ochoa CR, Zhou C, Toba M, Oka M, Annamdevula NS, Fitzgerald MS, Frank DW, Alvarez DF. Audia JP, et al. Among authors: alvarez df. PLoS One. 2013 Nov 27;8(11):e81792. doi: 10.1371/journal.pone.0081792. eCollection 2013. PLoS One. 2013. PMID: 24312357 Free PMC article.
The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury.
Stevens TC, Ochoa CD, Morrow KA, Robson MJ, Prasain N, Zhou C, Alvarez DF, Frank DW, Balczon R, Stevens T. Stevens TC, et al. Among authors: alvarez df. Am J Physiol Lung Cell Mol Physiol. 2014 May 15;306(10):L915-24. doi: 10.1152/ajplung.00135.2013. Epub 2014 Apr 4. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24705722 Free PMC article.
Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function.
Audia JP, Yang XM, Crockett ES, Housley N, Haq EU, O'Donnell K, Cohen MV, Downey JM, Alvarez DF. Audia JP, et al. Among authors: alvarez df. Basic Res Cardiol. 2018 Jul 10;113(5):32. doi: 10.1007/s00395-018-0692-z. Basic Res Cardiol. 2018. PMID: 29992382 Free PMC article.
Infection-induced endothelial amyloids impair memory.
Balczon R, Pittet JF, Wagener BM, Moser SA, Voth S, Vorhees CV, Williams MT, Bridges JP, Alvarez DF, Koloteva A, Xu Y, Zha XM, Audia JP, Stevens T, Lin MT. Balczon R, et al. Among authors: alvarez df. FASEB J. 2019 Sep;33(9):10300-10314. doi: 10.1096/fj.201900322R. Epub 2019 Jun 18. FASEB J. 2019. PMID: 31211919 Free PMC article.
71 results