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α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions.
Meacci G, Wolfenson H, Liu S, Stachowiak MR, Iskratsch T, Mathur A, Ghassemi S, Gauthier N, Tabdanov E, Lohner J, Gondarenko A, Chander AC, Roca-Cusachs P, O'Shaughnessy B, Hone J, Sheetz MP. Meacci G, et al. Among authors: liu s. Mol Biol Cell. 2016 Nov 7;27(22):3471-3479. doi: 10.1091/mbc.E16-02-0107. Epub 2016 Apr 27. Mol Biol Cell. 2016. PMID: 27122603 Free PMC article.
Cells test substrate rigidity by local contractions on submicrometer pillars.
Ghassemi S, Meacci G, Liu S, Gondarenko AA, Mathur A, Roca-Cusachs P, Sheetz MP, Hone J. Ghassemi S, et al. Among authors: liu s. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5328-33. doi: 10.1073/pnas.1119886109. Epub 2012 Mar 19. Proc Natl Acad Sci U S A. 2012. PMID: 22431603 Free PMC article.
EGFR and HER2 activate rigidity sensing only on rigid matrices.
Saxena M, Liu S, Yang B, Hajal C, Changede R, Hu J, Wolfenson H, Hone J, Sheetz MP. Saxena M, et al. Among authors: liu s. Nat Mater. 2017 Jul;16(7):775-781. doi: 10.1038/nmat4893. Epub 2017 May 1. Nat Mater. 2017. PMID: 28459445 Free PMC article.
Stopping transformed cancer cell growth by rigidity sensing.
Yang B, Wolfenson H, Chung VY, Nakazawa N, Liu S, Hu J, Huang RY, Sheetz MP. Yang B, et al. Among authors: liu s. Nat Mater. 2020 Feb;19(2):239-250. doi: 10.1038/s41563-019-0507-0. Epub 2019 Oct 28. Nat Mater. 2020. PMID: 31659296 Free PMC article.
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