Li Q - Search Results

1

Design, synthesis and antiproliferative activity of novel 5-nitropyrimidine-2,4-diamine derivatives bearing alkyl acetate moiety.

Zhao PL, Li YH, Yang HK, Chen P, Zhang B, Sun Q, Li Q, You WW. Zhao PL, et al. Among authors: li yh, li q. Eur J Med Chem. 2016 Aug 8;118:161-9. doi: 10.1016/j.ejmech.2016.04.038. Epub 2016 Apr 16. Eur J Med Chem. 2016. PMID: 27128180

2

Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives.

Zhao PL, Chen P, Li Q, Hu MJ, Diao PC, Pan ES, You WW. Zhao PL, et al. Among authors: li q. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3679-83. doi: 10.1016/j.bmcl.2016.05.086. Epub 2016 May 28. Bioorg Med Chem Lett. 2016. PMID: 27287368

3

Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues.

Li YH, Zhang B, Yang HK, Li Q, Diao PC, You WW, Zhao PL. Li YH, et al. Among authors: li q. Eur J Med Chem. 2017 Jan 5;125:1098-1106. doi: 10.1016/j.ejmech.2016.10.051. Epub 2016 Oct 24. Eur J Med Chem. 2017. PMID: 27810596

4

Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.

Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL. Diao PC, et al. Among authors: li q. Eur J Med Chem. 2017 Jul 7;134:110-118. doi: 10.1016/j.ejmech.2017.04.011. Epub 2017 Apr 7. Eur J Med Chem. 2017. PMID: 28410492

5

Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivatives.

Li Q, Yang HK, Sun Q, You WW, Zhao PL. Li Q, et al. Bioorg Med Chem Lett. 2017 Sep 1;27(17):3954-3958. doi: 10.1016/j.bmcl.2017.07.076. Epub 2017 Jul 29. Bioorg Med Chem Lett. 2017. PMID: 28789892

6

Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors.

Li Q, Jian XE, Chen ZR, Chen L, Huo XS, Li ZH, You WW, Rao JJ, Zhao PL. Li Q, et al. Among authors: li zh. Bioorg Chem. 2020 Sep;102:104076. doi: 10.1016/j.bioorg.2020.104076. Epub 2020 Jul 7. Bioorg Chem. 2020. PMID: 32683180

7

Synthesis and antiproliferative evaluation of novel 8-cyclopentyl-7,8-dihydropteridin-6(5H)-one derivatives as potential anticancer agents.

Li Q, Jian XE, Ma YF, Chen L, Huo XS, Wang Y, He RX, You WW, Zhao PL. Li Q, et al. Bioorg Med Chem Lett. 2021 Jan 1;31:127684. doi: 10.1016/j.bmcl.2020.127684. Epub 2020 Nov 13. Bioorg Med Chem Lett. 2021. PMID: 33197548

8

Design, synthesis and antiproliferative activity of novel 2,4-diamino-5-methyleneaminopyrimidine derivatives as potential anticancer agents.

Li Q, Chen L, Jian XE, Lv DX, You WW, Zhao PL. Li Q, et al. Bioorg Med Chem Lett. 2021 Sep 1;47:128213. doi: 10.1016/j.bmcl.2021.128213. Epub 2021 Jun 19. Bioorg Med Chem Lett. 2021. PMID: 34157389

9

Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity.

Li Q, Chen L, Ma YF, Jian XE, Ji JH, You WW, Zhao PL. Li Q, et al. Bioorg Chem. 2021 Nov;116:105324. doi: 10.1016/j.bioorg.2021.105324. Epub 2021 Sep 2. Bioorg Chem. 2021. PMID: 34509794

10

Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.

Li J, Zhang C, Xu H, Wang C, Dong R, Shen H, Zhuang X, Chen X, Li Q, Lu J, Zhang M, Wu X, Loomes KM, Zhou Y, Zhang Y, Liu J, Xu Y. Li J, et al. Among authors: li q. J Med Chem. 2022 Apr 14;65(7):5760-5799. doi: 10.1021/acs.jmedchem.2c00100. Epub 2022 Mar 25. J Med Chem. 2022. PMID: 35333526

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