Epstein JA - Search Results

1

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain.

He S, Mansour MR, Zimmerman MW, Ki DH, Layden HM, Akahane K, Gjini E, de Groh ED, Perez-Atayde AR, Zhu S, Epstein JA, Look AT. He S, et al. Among authors: epstein ja. Elife. 2016 Apr 27;5:e14713. doi: 10.7554/eLife.14713. Elife. 2016. PMID: 27130733 Free PMC article.

2

The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice.

Ismat FA, Xu J, Lu MM, Epstein JA. Ismat FA, et al. Among authors: epstein ja. J Clin Invest. 2006 Sep;116(9):2378-84. doi: 10.1172/JCI28341. Epub 2006 Aug 10. J Clin Invest. 2006. PMID: 16906226 Free PMC article.

3

NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.

Xu J, Ismat FA, Wang T, Yang J, Epstein JA. Xu J, et al. Among authors: epstein ja. Circulation. 2007 Nov 6;116(19):2148-56. doi: 10.1161/CIRCULATIONAHA.107.707752. Epub 2007 Oct 22. Circulation. 2007. PMID: 17967772

4

Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.

Xu J, Ismat FA, Wang T, Lu MM, Antonucci N, Epstein JA. Xu J, et al. Among authors: epstein ja. Circ Res. 2009 Jul 31;105(3):304-11. doi: 10.1161/CIRCRESAHA.109.201509. Epub 2009 Jul 2. Circ Res. 2009. PMID: 19574548 Free PMC article.

5

Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI.

Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA. Padmanabhan A, et al. Among authors: epstein ja. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22305-10. doi: 10.1073/pnas.0901932106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2009. PMID: 19966217 Free PMC article.

6

Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor gene.

Lee JS, Padmanabhan A, Shin J, Zhu S, Guo F, Kanki JP, Epstein JA, Look AT. Lee JS, et al. Among authors: epstein ja. Hum Mol Genet. 2010 Dec 1;19(23):4643-53. doi: 10.1093/hmg/ddq395. Epub 2010 Sep 21. Hum Mol Genet. 2010. PMID: 20858602 Free PMC article.

7

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development.

Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT. Shin J, et al. Among authors: epstein ja. Dis Model Mech. 2012 Nov;5(6):881-94. doi: 10.1242/dmm.009779. Epub 2012 Jul 5. Dis Model Mech. 2012. PMID: 22773753 Free PMC article.

8

Modulation of cAMP and ras signaling pathways improves distinct behavioral deficits in a zebrafish model of neurofibromatosis type 1.

Wolman MA, de Groh ED, McBride SM, Jongens TA, Granato M, Epstein JA. Wolman MA, et al. Among authors: epstein ja. Cell Rep. 2014 Sep 11;8(5):1265-70. doi: 10.1016/j.celrep.2014.07.054. Epub 2014 Aug 28. Cell Rep. 2014. PMID: 25176649 Free PMC article.

9

Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.

Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA. Yzaguirre AD, et al. Among authors: epstein ja. Elife. 2015 Oct 13;4:e07780. doi: 10.7554/eLife.07780. Elife. 2015. PMID: 26460546 Free PMC article.

10

H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis.

Poleshko A, Smith CL, Nguyen SC, Sivaramakrishnan P, Wong KG, Murray JI, Lakadamyali M, Joyce EF, Jain R, Epstein JA. Poleshko A, et al. Among authors: epstein ja. Elife. 2019 Oct 1;8:e49278. doi: 10.7554/eLife.49278. Elife. 2019. PMID: 31573510 Free PMC article.

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