Zhang A - Search Results

1

An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core.

Song Z, Xia Z, Ji Y, Xing L, Gao Y, Ai J, Geng M, Zhang A. Song Z, et al. Among authors: zhang a. Eur J Med Chem. 2016 Aug 8;118:244-9. doi: 10.1016/j.ejmech.2016.04.046. Epub 2016 Apr 19. Eur J Med Chem. 2016. PMID: 27131066

2

Advances in development of dopaminergic aporphinoids.

Zhang A, Zhang Y, Branfman AR, Baldessarini RJ, Neumeyer JL. Zhang A, et al. Among authors: zhang y. J Med Chem. 2007 Jan 25;50(2):171-81. doi: 10.1021/jm060959i. J Med Chem. 2007. PMID: 17228858 Review. No abstract available.

3

Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.

Liu Z, Zhang H, Ye N, Zhang J, Wu Q, Sun P, Li L, Zhen X, Zhang A. Liu Z, et al. Among authors: zhang a, zhang j, zhang h. J Med Chem. 2010 Feb 11;53(3):1319-28. doi: 10.1021/jm9015763. J Med Chem. 2010. PMID: 20041669

4

Synthesis and c-Met kinase inhibition of 3,5-disubstituted and 3,5,7-trisubstituted quinolines: identification of 3-(4-acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7- (trifluoromethyl)quinoline as a novel anticancer agent.

Wang Y, Ai J, Wang Y, Chen Y, Wang L, Liu G, Geng M, Zhang A. Wang Y, et al. Among authors: zhang a. J Med Chem. 2011 Apr 14;54(7):2127-42. doi: 10.1021/jm101340q. Epub 2011 Mar 15. J Med Chem. 2011. PMID: 21405128

5

Discovery of novel c-Met kinase inhibitors bearing a thieno[2,3-d]pyrimidine or furo[2,3-d]pyrimidine scaffold.

Zhao A, Gao X, Wang Y, Ai J, Wang Y, Chen Y, Geng M, Zhang A. Zhao A, et al. Among authors: zhang a. Bioorg Med Chem. 2011 Jul 1;19(13):3906-18. doi: 10.1016/j.bmc.2011.05.038. Epub 2011 May 24. Bioorg Med Chem. 2011. PMID: 21665484

6

Expeditious one-pot synthesis of C3-piperazinyl-substituted quinolines: key precursors to potent c-Met inhibitors.

Wang Y, Ai J, Liu G, Geng M, Zhang A. Wang Y, et al. Among authors: zhang a. Org Biomol Chem. 2011 Sep 7;9(17):5930-3. doi: 10.1039/c1ob05830d. Epub 2011 Jul 25. Org Biomol Chem. 2011. PMID: 21785792

7

Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: synthesis and SAR study as tyrosine kinase c-Met inhibitors.

Wu K, Ai J, Liu Q, Chen T, Zhao A, Peng X, Wang Y, Ji Y, Yao Q, Xu Y, Geng M, Zhang A. Wu K, et al. Among authors: zhang a. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6368-72. doi: 10.1016/j.bmcl.2012.08.075. Epub 2012 Aug 27. Bioorg Med Chem Lett. 2012. PMID: 22985853

8

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors.

Ye N, Chen CH, Chen T, Song Z, He JX, Huan XJ, Song SS, Liu Q, Chen Y, Ding J, Xu Y, Miao ZH, Zhang A. Ye N, et al. Among authors: zhang a. J Med Chem. 2013 Apr 11;56(7):2885-903. doi: 10.1021/jm301825t. Epub 2013 Mar 21. J Med Chem. 2013. PMID: 23473053

9

Dual ligands targeting dopamine D2 and serotonin 5-HT1A receptors as new antipsychotical or anti-Parkinsonian agents.

Ye N, Song Z, Zhang A. Ye N, et al. Among authors: zhang a. Curr Med Chem. 2014;21(4):437-57. doi: 10.2174/09298673113206660300. Curr Med Chem. 2014. PMID: 24164194 Review.

10

Palladium-catalyzed double C-H activation: one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides.

Fan Z, Wu K, Xing L, Yao Q, Zhang A. Fan Z, et al. Among authors: zhang a. Chem Commun (Camb). 2014 Feb 18;50(14):1682-4. doi: 10.1039/c3cc47989g. Epub 2014 Jan 6. Chem Commun (Camb). 2014. PMID: 24394189

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