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Page 1
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.
Tosatto A, Sommaggio R, Kummerow C, Bentham RB, Blacker TS, Berecz T, Duchen MR, Rosato A, Bogeski I, Szabadkai G, Rizzuto R, Mammucari C. Tosatto A, et al. Among authors: bentham rb. EMBO Mol Med. 2016 May 2;8(5):569-85. doi: 10.15252/emmm.201606255. Print 2016 May. EMBO Mol Med. 2016. PMID: 27138568 Free PMC article.
No evidence for a local renin-angiotensin system in liver mitochondria.
Astin R, Bentham R, Djafarzadeh S, Horscroft JA, Kuc RE, Leung PS, Skipworth JR, Vicencio JM, Davenport AP, Murray AJ, Takala J, Jakob SM, Montgomery H, Szabadkai G. Astin R, et al. Sci Rep. 2013;3:2467. doi: 10.1038/srep02467. Sci Rep. 2013. PMID: 23959064 Free PMC article.
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway.
Wilcz-Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R, Uhlik L, Bentham RB, Godinho SA, Dalli J, Grose R, Szabadkai G, Jones L, Hodivala-Dilke K, Bianchi K. Wilcz-Villega E, et al. Among authors: bentham rb. EMBO Mol Med. 2020 Feb 7;12(2):e10491. doi: 10.15252/emmm.201910491. Epub 2020 Jan 13. EMBO Mol Med. 2020. PMID: 31930708 Free PMC article.
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
Xu R, Jones W, Wilcz-Villega E, Costa AS, Rajeeve V, Bentham RB, Bryson K, Nagano A, Yaman B, Olendo Barasa S, Wang Y, Chelala C, Cutillas P, Szabadkai G, Frezza C, Bianchi K. Xu R, et al. Among authors: bentham rb. EMBO Rep. 2020 Sep 3;21(9):e48260. doi: 10.15252/embr.201948260. Epub 2020 Aug 11. EMBO Rep. 2020. PMID: 32783398 Free PMC article.
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response.
Desai R, East DA, Hardy L, Faccenda D, Rigon M, Crosby J, Alvarez MS, Singh A, Mainenti M, Hussey LK, Bentham R, Szabadkai G, Zappulli V, Dhoot GK, Romano LE, Xia D, Coppens I, Hamacher-Brady A, Chapple JP, Abeti R, Fleck RA, Vizcay-Barrena G, Smith K, Campanella M. Desai R, et al. Sci Adv. 2020 Dec 18;6(51):eabc9955. doi: 10.1126/sciadv.abc9955. Print 2020 Dec. Sci Adv. 2020. PMID: 33355129 Free PMC article.
Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham R, Litchfield K, Watkins TBK, Lim EL, Rosenthal R, Martínez-Ruiz C, Hiley CT, Bakir MA, Salgado R, Moore DA, Jamal-Hanjani M; TRACERx Consortium; Swanton C, McGranahan N. Bentham R, et al. Nature. 2021 Sep;597(7877):555-560. doi: 10.1038/s41586-021-03894-5. Epub 2021 Sep 8. Nature. 2021. PMID: 34497419
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Litchfield K, Reading JL, Puttick C, Thakkar K, Abbosh C, Bentham R, Watkins TBK, Rosenthal R, Biswas D, Rowan A, Lim E, Al Bakir M, Turati V, Guerra-Assunção JA, Conde L, Furness AJS, Saini SK, Hadrup SR, Herrero J, Lee SH, Van Loo P, Enver T, Larkin J, Hellmann MD, Turajlic S, Quezada SA, McGranahan N, Swanton C. Litchfield K, et al. Cell. 2021 Feb 4;184(3):596-614.e14. doi: 10.1016/j.cell.2021.01.002. Epub 2021 Jan 27. Cell. 2021. PMID: 33508232 Free PMC article.
18 results