Lu T - Search Results

1

Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors.

Zhang Z, Hou S, Chen H, Ran T, Jiang F, Bian Y, Zhang D, Zhi Y, Wang L, Zhang L, Li H, Zhang Y, Tang W, Lu T, Chen Y. Zhang Z, et al. Among authors: lu t. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2931-2935. doi: 10.1016/j.bmcl.2016.04.034. Epub 2016 Apr 22. Bioorg Med Chem Lett. 2016. PMID: 27142751

2

Pharmacophore identification of Raf-1 kinase inhibitors.

Zhu T, Jiao Y, Chen YD, Wang X, Li HF, Zhang LY, Lu T. Zhu T, et al. Among authors: lu t. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2346-50. doi: 10.1016/j.bmcl.2008.02.068. Epub 2008 Mar 4. Bioorg Med Chem Lett. 2008. PMID: 18346893

3

Virtual screening for Raf-1 kinase inhibitors based on pharmacophore model of substituted ureas.

Li HF, Lu T, Zhu T, Jiang YJ, Rao SS, Hu LY, Xin BT, Chen YD. Li HF, et al. Among authors: lu t. Eur J Med Chem. 2009 Mar;44(3):1240-9. doi: 10.1016/j.ejmech.2008.09.016. Epub 2008 Sep 23. Eur J Med Chem. 2009. PMID: 18947905

4

Mechanisms for chemical transformations of (R,R)-tartaric acid on Cu(110): A first principles study.

Zhang J, Lu T, Jiang C, Zou J, Cao F, Chen Y. Zhang J, et al. Among authors: lu t. J Chem Phys. 2009 Oct 14;131(14):144703. doi: 10.1063/1.3247188. J Chem Phys. 2009. PMID: 19831460

5

Structure-based and shape-complemented pharmacophore modeling for the discovery of novel checkpoint kinase 1 inhibitors.

Chen XM, Lu T, Lu S, Li HF, Yuan HL, Ran T, Liu HC, Chen YD. Chen XM, et al. Among authors: lu s, lu t. J Mol Model. 2010 Jul;16(7):1195-204. doi: 10.1007/s00894-009-0630-y. Epub 2009 Dec 18. J Mol Model. 2010. PMID: 20020310

6

Investigation on the isoform selectivity of histone deacetylase inhibitors using chemical feature based pharmacophore and docking approaches.

Zhu Y, Li HF, Lu S, Zheng YX, Wu Z, Tang WF, Zhou X, Lu T. Zhu Y, et al. Among authors: lu s, lu t. Eur J Med Chem. 2010 May;45(5):1777-91. doi: 10.1016/j.ejmech.2010.01.010. Epub 2010 Jan 28. Eur J Med Chem. 2010. PMID: 20153566

7

Recent advances in the research and development of B-Raf inhibitors.

Li HF, Chen Y, Rao SS, Chen XM, Liu HC, Qin JH, Tang WF, Yue-Wang, Zhou X, Lu T. Li HF, et al. Among authors: lu t. Curr Med Chem. 2010;17(16):1618-34. doi: 10.2174/092986710791111242. Curr Med Chem. 2010. PMID: 20345352 Review.

8

A facile synthesis of 3-substituted 9H-pyrido[3,4-b]indol-1(2H)-one derivatives from 3-substituted beta-carbolines.

Lin G, Wang Y, Zhou Q, Tang W, Wang J, Lu T. Lin G, et al. Among authors: lu t. Molecules. 2010 Aug 17;15(8):5680-91. doi: 10.3390/molecules15085680. Molecules. 2010. PMID: 20717074 Free PMC article.

9

Novel strategy for three-dimensional fragment-based lead discovery.

Yuan H, Lu T, Ran T, Liu H, Lu S, Tai W, Leng Y, Zhang W, Wang J, Chen Y. Yuan H, et al. Among authors: lu s, lu t. J Chem Inf Model. 2011 Apr 25;51(4):959-74. doi: 10.1021/ci200003c. Epub 2011 Mar 25. J Chem Inf Model. 2011. PMID: 21438547

10

A selectivity study on mTOR/PI3Kα inhibitors by homology modeling and 3D-QSAR.

Ran T, Lu T, Yuan H, Liu H, Wang J, Zhang W, Leng Y, Lin G, Zhuang S, Chen Y. Ran T, et al. Among authors: lu t. J Mol Model. 2012 Jan;18(1):171-86. doi: 10.1007/s00894-011-1034-3. Epub 2011 Apr 27. J Mol Model. 2012. PMID: 21523553

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