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Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.
Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A. Marangoni F, et al. Among authors: naldini l. Mol Ther. 2009 Jun;17(6):1073-82. doi: 10.1038/mt.2009.31. Epub 2009 Mar 3. Mol Ther. 2009. PMID: 19259069 Free PMC article.
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy.
Montini E, Cesana D, Schmidt M, Sanvito F, Bartholomae CC, Ranzani M, Benedicenti F, Sergi LS, Ambrosi A, Ponzoni M, Doglioni C, Di Serio C, von Kalle C, Naldini L. Montini E, et al. Among authors: naldini l. J Clin Invest. 2009 Apr;119(4):964-75. doi: 10.1172/JCI37630. Epub 2009 Mar 23. J Clin Invest. 2009. PMID: 19307726 Free PMC article.
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.
Pucci F, Venneri MA, Biziato D, Nonis A, Moi D, Sica A, Di Serio C, Naldini L, De Palma M. Pucci F, et al. Among authors: naldini l. Blood. 2009 Jul 23;114(4):901-14. doi: 10.1182/blood-2009-01-200931. Epub 2009 Apr 21. Blood. 2009. PMID: 19383967 Free article.
Angiopoietin-2 TIEs up macrophages in tumor angiogenesis.
De Palma M, Naldini L. De Palma M, et al. Among authors: naldini l. Clin Cancer Res. 2011 Aug 15;17(16):5226-32. doi: 10.1158/1078-0432.CCR-10-0171. Epub 2011 May 16. Clin Cancer Res. 2011. PMID: 21576085
miR-511-3p modulates genetic programs of tumor-associated macrophages.
Squadrito ML, Pucci F, Magri L, Moi D, Gilfillan GD, Ranghetti A, Casazza A, Mazzone M, Lyle R, Naldini L, De Palma M. Squadrito ML, et al. Among authors: naldini l. Cell Rep. 2012 Feb 23;1(2):141-54. doi: 10.1016/j.celrep.2011.12.005. Epub 2012 Feb 9. Cell Rep. 2012. PMID: 22832163 Free article.
313 results