de Lera ÁR - Search Results

1

An Endogenous Mammalian Retinoid X Receptor Ligand, At Last!

de Lera ÁR, Krezel W, Rühl R. de Lera ÁR, et al. ChemMedChem. 2016 May 19;11(10):1027-37. doi: 10.1002/cmdc.201600105. Epub 2016 May 6. ChemMedChem. 2016. PMID: 27151148

2

Design of selective nuclear receptor modulators: RAR and RXR as a case study.

de Lera AR, Bourguet W, Altucci L, Gronemeyer H. de Lera AR, et al. Nat Rev Drug Discov. 2007 Oct;6(10):811-20. doi: 10.1038/nrd2398. Nat Rev Drug Discov. 2007. PMID: 17906643 Review.

3

Highly potent naphthofuran-based retinoic acid receptor agonists.

Santín EP, Khanwalkar H, Voegel J, Collette P, Mauvais P, Gronemeyer H, de Lera AR. Santín EP, et al. Among authors: de lera ar. ChemMedChem. 2009 May;4(5):780-91. doi: 10.1002/cmdc.200900015. ChemMedChem. 2009. PMID: 19350615

4

C3 halogen and c8'' substituents on stilbene arotinoids modulate retinoic Acid receptor subtype function.

Alvarez S, Khanwalkar H, Alvarez R, Erb C, Martínez C, Rodríguez-Barrios F, Germain P, Gronemeyer H, de Lera AR. Alvarez S, et al. Among authors: de lera ar. ChemMedChem. 2009 Oct;4(10):1630-40. doi: 10.1002/cmdc.200900214. ChemMedChem. 2009. PMID: 19670208

5

New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators.

Souto JA, Benedetti R, Otto K, Miceli M, Alvarez R, Altucci L, de Lera AR. Souto JA, et al. Among authors: de lera ar. ChemMedChem. 2010 Sep 3;5(9):1530-40. doi: 10.1002/cmdc.201000158. ChemMedChem. 2010. PMID: 20683922

6

Retinoid x receptor gamma is implicated in docosahexaenoic acid modulation of despair behaviors and working memory in mice.

Wietrzych-Schindler M, Szyszka-Niagolov M, Ohta K, Endo Y, Pérez E, de Lera AR, Chambon P, Krezel W. Wietrzych-Schindler M, et al. Among authors: de lera ar. Biol Psychiatry. 2011 Apr 15;69(8):788-94. doi: 10.1016/j.biopsych.2010.12.017. Epub 2011 Feb 21. Biol Psychiatry. 2011. PMID: 21334601

7

Design and stereoselective synthesis of retinoids with ferrocene or N-butylcarbazole pharmacophores that induce post-differentiation apoptosis in acute promyelocytic leukemia cells.

Ivanova D, Gronemeyer H, de Lera AR. Ivanova D, et al. Among authors: de lera ar. ChemMedChem. 2011 Aug 1;6(8):1518-29. doi: 10.1002/cmdc.201100065. Epub 2011 Apr 19. ChemMedChem. 2011. PMID: 21506276

8

Modulation of RXR function through ligand design.

Pérez E, Bourguet W, Gronemeyer H, de Lera AR. Pérez E, et al. Among authors: de lera ar. Biochim Biophys Acta. 2012 Jan;1821(1):57-69. doi: 10.1016/j.bbalip.2011.04.003. Epub 2011 Apr 16. Biochim Biophys Acta. 2012. PMID: 21515403 Review.

9

A DNA methyltransferase modulator inspired by peyssonenyne natural product structures.

García-Domínguez P, Weiss M, Lepore I, Álvarez R, Altucci L, Gronemeyer H, de Lera ÁR. García-Domínguez P, et al. Among authors: de lera ar. ChemMedChem. 2012 Dec;7(12):2101-12. doi: 10.1002/cmdc.201200366. Epub 2012 Oct 9. ChemMedChem. 2012. PMID: 23047325

10

Regulation of retinoid-mediated signaling involved in skin homeostasis by RAR and RXR agonists/antagonists in mouse skin.

Gericke J, Ittensohn J, Mihály J, Alvarez S, Alvarez R, Töröcsik D, de Lera AR, Rühl R. Gericke J, et al. Among authors: de lera ar. PLoS One. 2013 Apr 24;8(4):e62643. doi: 10.1371/journal.pone.0062643. Print 2013. PLoS One. 2013. PMID: 23638129 Free PMC article.

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