Saini V - Search Results

1

Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.

Maqbool M, Manral A, Jameel E, Kumar J, Saini V, Shandilya A, Tiwari M, Hoda N, Jayaram B. Maqbool M, et al. Among authors: saini v. Bioorg Med Chem. 2016 Jun 15;24(12):2777-88. doi: 10.1016/j.bmc.2016.04.041. Epub 2016 Apr 22. Bioorg Med Chem. 2016. PMID: 27157006

2

Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.

Manral A, Saini V, Meena P, Tiwari M. Manral A, et al. Among authors: saini v. Bioorg Med Chem. 2015 Oct 1;23(19):6389-403. doi: 10.1016/j.bmc.2015.08.024. Epub 2015 Aug 22. Bioorg Med Chem. 2015. PMID: 26337018

3

Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-β-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease.

Mishra CB, Manral A, Kumari S, Saini V, Tiwari M. Mishra CB, et al. Among authors: saini v. Bioorg Med Chem. 2016 Aug 15;24(16):3829-41. doi: 10.1016/j.bmc.2016.06.027. Epub 2016 Jun 14. Bioorg Med Chem. 2016. PMID: 27353888

4

Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.

Mishra CB, Kumari S, Manral A, Prakash A, Saini V, Lynn AM, Tiwari M. Mishra CB, et al. Among authors: saini v. Eur J Med Chem. 2017 Jan 5;125:736-750. doi: 10.1016/j.ejmech.2016.09.057. Epub 2016 Sep 19. Eur J Med Chem. 2017. PMID: 27721157

5

Protective effects of a piperazine derivative [N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-phenyl} carbamic acid ethyl ester] against aluminium-induced neurotoxicity: insights from in silico and in vivo studies.

Meena P, Manral A, Saini V, Tiwari M. Meena P, et al. Among authors: saini v. Neurotox Res. 2015 Apr;27(3):314-27. doi: 10.1007/s12640-014-9499-3. Epub 2014 Nov 18. Neurotox Res. 2015. PMID: 25403519

6

DADS Analogues Ameliorated the Cognitive Impairments of Alzheimer-Like Rat Model Induced by Scopolamine.

Manral A, Meena P, Saini V, Siraj F, Shalini S, Tiwari M. Manral A, et al. Among authors: saini v. Neurotox Res. 2016 Oct;30(3):407-26. doi: 10.1007/s12640-016-9625-5. Epub 2016 May 5. Neurotox Res. 2016. PMID: 27149969

7

Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells.

Saini V, Manral A, Arora R, Meena P, Gusain S, Saluja D, Tiwari M. Saini V, et al. Pharmacol Rep. 2017 Aug;69(4):813-821. doi: 10.1016/j.pharep.2017.03.006. Epub 2017 Mar 14. Pharmacol Rep. 2017. PMID: 28591670

8

Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension.

Sharma DK, Manral A, Saini V, Singh A, Srinivasan BP, Tiwari M. Sharma DK, et al. Among authors: saini v. Eur J Pharmacol. 2012 Sep 15;691(1-3):198-208. doi: 10.1016/j.ejphar.2012.07.022. Epub 2012 Jul 20. Eur J Pharmacol. 2012. PMID: 22819707

9

Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1.

Arora R, Sawney S, Saini V, Steffi C, Tiwari M, Saluja D. Arora R, et al. Among authors: saini v. Mol Cancer. 2016 Oct 18;15(1):64. doi: 10.1186/s12943-016-0550-2. Mol Cancer. 2016. PMID: 27756327 Free PMC article.

10

The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions.

Saini V, Staren DM, Ziarek JJ, Nashaat ZN, Campbell EM, Volkman BF, Marchese A, Majetschak M. Saini V, et al. J Biol Chem. 2011 Sep 23;286(38):33466-77. doi: 10.1074/jbc.M111.233742. Epub 2011 Jul 13. J Biol Chem. 2011. PMID: 21757744 Free PMC article.

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