Gan Z - Search Results

1

Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral κ-opioid receptor agonists.

Guo T, Gan Z, Chen J, Wang D, He L, Song Q, Xu Y. Guo T, et al. Among authors: gan z. Bioorg Med Chem. 2016 Jul 1;24(13):2964-2970. doi: 10.1016/j.bmc.2016.05.002. Epub 2016 May 3. Bioorg Med Chem. 2016. PMID: 27185012

2

Discovery of novel 9H-purin derivatives as dual inhibitors of HDAC1 and CDK2.

Yu Y, Ran D, Jiang J, Pan T, Dan Y, Tang Q, Li W, Zhang L, Gan L, Gan Z. Yu Y, et al. Among authors: gan z, gan l. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2136-2140. doi: 10.1016/j.bmcl.2019.06.059. Epub 2019 Jun 29. Bioorg Med Chem Lett. 2019. PMID: 31272794

3

Tetrazanbigen Derivatives as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Partial Agonists: Design, Synthesis, Structure-Activity Relationship, and Anticancer Activities.

Gan L, Gan Z, Dan Y, Li Y, Zhang P, Chen S, Ye Z, Pan T, Wan C, Hu X, Yu Y. Gan L, et al. Among authors: gan z. J Med Chem. 2021 Jan 28;64(2):1018-1036. doi: 10.1021/acs.jmedchem.0c01512. Epub 2021 Jan 10. J Med Chem. 2021. PMID: 33423463

4

Discovery of 2,4-pyrimidinediamine derivatives as potent dual inhibitors of ALK and HDAC.

Pan T, Dan Y, Guo D, Jiang J, Ran D, Zhang L, Tian B, Yuan J, Yu Y, Gan Z. Pan T, et al. Among authors: gan z. Eur J Med Chem. 2021 Nov 15;224:113672. doi: 10.1016/j.ejmech.2021.113672. Epub 2021 Jun 29. Eur J Med Chem. 2021. PMID: 34237620

5

Design, synthesis and biological evaluation of 2,4-pyrimidinediamine derivatives as ALK and HDACs dual inhibitors for the treatment of ALK addicted cancer.

Guo D, Yu Y, Long B, Deng P, Ran D, Han L, Zheng J, Gan Z. Guo D, et al. Among authors: gan z. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2512-2529. doi: 10.1080/14756366.2022.2121822. J Enzyme Inhib Med Chem. 2022. PMID: 36100230 Free PMC article.

6

Design, synthesis, and biological evaluation of naphthalene imidazo[1,2-b]pyridazine hybrid derivatives as VEGFR selective inhibitors.

Wang S, Gan L, Han L, Deng P, Li Y, He D, Chi H, Zhu L, Li Y, Long R, Gan Z. Wang S, et al. Among authors: gan z, gan l. Arch Pharm (Weinheim). 2024 Oct;357(10):e2400411. doi: 10.1002/ardp.202400411. Epub 2024 Jul 15. Arch Pharm (Weinheim). 2024. PMID: 39008876

7

TNBG-5602, a novel derivative of quinoxaline, inhibits liver cancer growth via upregulating peroxisome proliferator-activated receptor γ in vitro and in vivo.

Hu X, Wan C, Gan Z, Liu R, Chen Y, Wang J, Gan L, Chen Y, Li Y, He B, Yu Y. Hu X, et al. Among authors: gan z, gan l. J Pharm Pharmacol. 2019 Nov;71(11):1684-1694. doi: 10.1111/jphp.13159. Epub 2019 Aug 25. J Pharm Pharmacol. 2019. PMID: 31446646

8

T-17, a novel cyclin-dependent kinases/histone deacetylases dual inhibitor, induces cancer cells death through cell cycle arrest and apoptosis.

Zhang L, Long R, Li X, Jiang J, Chen H, Tian B, Long B, Yu Y, Gan Z. Zhang L, et al. Among authors: gan z. Drug Dev Res. 2022 Nov;83(7):1578-1588. doi: 10.1002/ddr.21977. Epub 2022 Jul 17. Drug Dev Res. 2022. PMID: 35844039

9

N76-1, a novel CDK7 inhibitor, exhibits potent anti-cancer effects in triple negative breast cancer.

Zhang L, Wu L, Zhou D, Wang G, Chen B, Shen Z, Li X, Wu Q, Qu N, Wu Y, Yuan L, Gan Z, Zhou W. Zhang L, et al. Among authors: gan z. Eur J Pharmacol. 2023 Sep 15;955:175892. doi: 10.1016/j.ejphar.2023.175892. Epub 2023 Jul 8. Eur J Pharmacol. 2023. PMID: 37429520 Free article.

10

A Glimepiride-Metformin Multidrug Crystal: Synthesis, Crystal Structure Analysis, and Physicochemical Properties.

Bian X, Jiang L, Gan Z, Guan X, Zhang L, Cai L, Hu X. Bian X, et al. Among authors: gan z. Molecules. 2019 Oct 21;24(20):3786. doi: 10.3390/molecules24203786. Molecules. 2019. PMID: 31640214 Free PMC article.

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