He L - Search Results

1

Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral κ-opioid receptor agonists.

Guo T, Gan Z, Chen J, Wang D, He L, Song Q, Xu Y. Guo T, et al. Among authors: he l. Bioorg Med Chem. 2016 Jul 1;24(13):2964-2970. doi: 10.1016/j.bmc.2016.05.002. Epub 2016 May 3. Bioorg Med Chem. 2016. PMID: 27185012

2

Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex.

Wang WS, Kang S, Liu WT, Li M, Liu Y, Yu C, Chen J, Chi ZQ, He L, Liu JG. Wang WS, et al. Among authors: he l. J Neurosci. 2012 Oct 3;32(40):13763-75. doi: 10.1523/JNEUROSCI.1991-12.2012. J Neurosci. 2012. PMID: 23035088 Free PMC article.

3

The role of the dynorphin/κ opioid receptor system in anxiety.

Hang A, Wang YJ, He L, Liu JG. Hang A, et al. Among authors: he l. Acta Pharmacol Sin. 2015 Jul;36(7):783-90. doi: 10.1038/aps.2015.32. Epub 2015 May 18. Acta Pharmacol Sin. 2015. PMID: 25982631 Free PMC article. Review.

4

Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.

Mao PT, He WB, Mai X, Feng LH, Li N, Liao YJ, Zhu CS, Li J, Chen T, Liu SH, Zhang QM, He L. Mao PT, et al. Among authors: he wb, he l. Bioorg Med Chem. 2022 Feb 15;56:116599. doi: 10.1016/j.bmc.2021.116599. Epub 2021 Dec 31. Bioorg Med Chem. 2022. PMID: 35041998

5

High throughput screening and structure-activity relationship study of potential α2A-adrenoceptor agonists by LANCETM cAMP assay.

Yang H, He L, Yan M, He JG, Yu T. Yang H, et al. Among authors: he jg, he l. Comb Chem High Throughput Screen. 2013 Jun 28;16(7):522-30. doi: 10.2174/1386207311316070003. Comb Chem High Throughput Screen. 2013. PMID: 23514320

6

A cell-based, high-throughput homogeneous time-resolved fluorescence assay for the screening of potential κ-opioid receptor agonists.

Wang Y, Yan M, Zheng GY, He L, Yang H. Wang Y, et al. Among authors: he l. Acta Pharmacol Sin. 2014 Jul;35(7):957-66. doi: 10.1038/aps.2014.21. Epub 2014 Jun 16. Acta Pharmacol Sin. 2014. PMID: 24930486 Free PMC article.

7

κ Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice.

Wang YJ, Hang A, Lu YC, Long Y, Zan GY, Li XP, Wang Q, Zhao ZX, He L, Chi ZQ, Liu JG. Wang YJ, et al. Among authors: he l. Neuropharmacology. 2016 Nov;110(Pt A):92-101. doi: 10.1016/j.neuropharm.2016.04.022. Epub 2016 Apr 20. Neuropharmacology. 2016. PMID: 27106167

8

Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile.

Wu C, Wang Y, Yang F, Shi W, Wang Z, He L, He Y, Shen J. Wu C, et al. Among authors: he y, he l. ChemMedChem. 2019 Dec 17;14(24):2042-2051. doi: 10.1002/cmdc.201900439. Epub 2019 Nov 20. ChemMedChem. 2019. PMID: 31746558

9

Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease.

Sun Y, Huang J, Chen Y, Shang H, Zhang W, Yu J, He L, Xing C, Zhuang C. Sun Y, et al. Among authors: he l. Bioorg Chem. 2020 Oct;103:104172. doi: 10.1016/j.bioorg.2020.104172. Epub 2020 Aug 27. Bioorg Chem. 2020. PMID: 32890991

10

TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia.

Wang Y, He Y, Yang F, Abame MA, Wu C, Peng Y, Feng L, Shen J, Wang Z, He L. Wang Y, et al. Among authors: he y, he l. J Pharmacol Exp Ther. 2021 Jul;378(1):20-30. doi: 10.1124/jpet.120.000414. Epub 2021 May 11. J Pharmacol Exp Ther. 2021. PMID: 33975897

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