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Page 1
Pharmacokinetics of darunavir in fixed-dose combination with cobicistat compared with coadministration of darunavir and ritonavir as single agents in healthy volunteers.
Kakuda TN, Opsomer M, Timmers M, Iterbeke K, Van De Casteele T, Hillewaert V, Petrovic R, Hoetelmans RM. Kakuda TN, et al. Among authors: hillewaert v. J Clin Pharmacol. 2014 Aug;54(8):949-57. doi: 10.1002/jcph.290. Epub 2014 Mar 26. J Clin Pharmacol. 2014. PMID: 24644095 Clinical Trial.
Single- and multiple-dose pharmacokinetics and safety of pimodivir, a novel, non-nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open-label study in healthy volunteers.
Deleu S, Kakuda TN, Spittaels K, Vercauteren JJ, Hillewaert V, Lwin A, Leopold L, Hoetelmans RMW. Deleu S, et al. Among authors: hillewaert v. Br J Clin Pharmacol. 2018 Nov;84(11):2663-2672. doi: 10.1111/bcp.13733. Epub 2018 Sep 14. Br J Clin Pharmacol. 2018. PMID: 30098042 Free PMC article. Clinical Trial.
JNJ-73763989 pharmacokinetics and safety: Liver-targeted siRNAs against hepatitis B virus, in Japanese and non-Japanese healthy adults, and combined with JNJ-56136379 and a nucleos(t)ide analogue in patients with chronic hepatitis B.
Gane E, Yuen MF, Kakuda TN, Ogawa T, Takahashi Y, Goeyvaerts N, Lonjon-Domanec I, Vaughan T, Schluep T, Hamilton J, Njumbe Ediage E, Hillewaert V, Snoeys J, Lenz O, Talloen W, Biermer M. Gane E, et al. Among authors: hillewaert v. Antivir Ther. 2022 Jun;27(3):13596535221093856. doi: 10.1177/13596535221093856. Antivir Ther. 2022. PMID: 35695169 Free article. Clinical Trial.
Drug-Drug Interactions With the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379 (Bersacapavir).
Vandenbossche J, Yogaratnam J, Hillewaert V, Rasschaert F, Talloen W, Biewenga J, Snoeys J, Kakuda TN, Palmer M, Nangosyah J, Biermer M. Vandenbossche J, et al. Among authors: hillewaert v. Clin Pharmacol Drug Dev. 2022 Dec;11(12):1419-1429. doi: 10.1002/cpdd.1164. Epub 2022 Sep 5. Clin Pharmacol Drug Dev. 2022. PMID: 36062869 Free PMC article. Clinical Trial.
Pharmacokinetics of JNJ-73763989 and JNJ-56136379 (Bersacapavir) in Participants With Moderate Hepatic Impairment.
Kakuda TN, Halabi A, Klein G, Sanga M, Guinard-Azadian C, Kowalik M, Nedoschinsky K, Nangosyah J, Ediage EN, Hillewaert V, Verboven P, Goris I, Snoeys J, Palmer M, Biermer M. Kakuda TN, et al. Among authors: hillewaert v. J Clin Pharmacol. 2023 Jun;63(6):732-741. doi: 10.1002/jcph.2214. Epub 2023 Mar 20. J Clin Pharmacol. 2023. PMID: 36786053
A high-performance liquid chromatography-tandem mass spectrometry method for the determination of artemether and dihydroartemisinin in human plasma.
Hilhorst MJ, Hendriks G, de Vries R, Hillewaert V, Verhaege T, van de Merbel NC. Hilhorst MJ, et al. Among authors: hillewaert v. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 15;965:45-53. doi: 10.1016/j.jchromb.2014.06.006. Epub 2014 Jun 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24996069
18 results