Nakai T - Search Results

1

Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.

Nakai T, Perl NR, Barden TC, Carvalho A, Fretzen A, Germano P, Im GY, Jin H, Kim C, Lee TW, Long K, Moore J, Rohde JM, Sarno R, Segal C, Solberg EO, Tobin J, Zimmer DP, Currie MG. Nakai T, et al. ACS Med Chem Lett. 2016 Feb 24;7(5):465-9. doi: 10.1021/acsmedchemlett.5b00479. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190594 Free PMC article.

2

Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator.

Rennie GR, Barden TC, Bernier SG, Carvalho A, Deming R, Germano P, Hudson C, Im GJ, Iyengar RR, Jia L, Jung J, Kim E, Lee TW, Mermerian A, Moore J, Nakai T, Perl NR, Tobin J, Zimmer DP, Renhowe PA. Rennie GR, et al. Among authors: nakai t. Bioorg Med Chem Lett. 2021 May 15;40:127886. doi: 10.1016/j.bmcl.2021.127886. Epub 2021 Mar 2. Bioorg Med Chem Lett. 2021. PMID: 33662540

3

Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase.

Wales JA, Chen CY, Breci L, Weichsel A, Bernier SG, Sheppeck JE 2nd, Solinga R, Nakai T, Renhowe PA, Jung J, Montfort WR. Wales JA, et al. Among authors: nakai t. J Biol Chem. 2018 Feb 2;293(5):1850-1864. doi: 10.1074/jbc.RA117.000457. Epub 2017 Dec 8. J Biol Chem. 2018. PMID: 29222330 Free PMC article.

4

Enantioselective synthesis of protected amines by the catalytic asymmetric addition of hydrazoic acid to ketenes.

Dai X, Nakai T, Romero JA, Fu GC. Dai X, et al. Among authors: nakai t. Angew Chem Int Ed Engl. 2007;46(23):4367-9. doi: 10.1002/anie.200700697. Angew Chem Int Ed Engl. 2007. PMID: 17471484 No abstract available.

5

Population pharmacokinetic model of tranexamic acid in patients who undergo cardiac surgery with cardiopulmonary bypass.

Nakai T, Tamura T, Miyagawa Y, Inagaki T, Mutsuga M, Yamada S, Yamada K, Nishiwaki K, Mizoguchi H. Nakai T, et al. Eur J Clin Pharmacol. 2025 Jan 16. doi: 10.1007/s00228-025-03802-0. Online ahead of print. Eur J Clin Pharmacol. 2025. PMID: 39820511

6

Patient Education for CKD and Decision Support in Primary Care: Findings From the EPIK Pilot Study.

Nunes JW, Kerr E, Ojo A, Powell C, Fan A, Brinley FJ, Devine A, Ellies T, Grzyb K, Garcia-Guzman L, Nakai T, Oliverio A, Chen E, Fagerlin A. Nunes JW, et al. Among authors: nakai t. Am J Kidney Dis. 2024 Dec 13:S0272-6386(24)01117-X. doi: 10.1053/j.ajkd.2024.10.005. Online ahead of print. Am J Kidney Dis. 2024. PMID: 39675547

7

Risk Reduction of Severe Anastomotic Leakage by Evaluation of Blood Perfusion Using Indocyanine Green After Minimally Invasive Esophagectomy Followed by Narrow Gastric Tube Reconstruction.

Kitadani J, Hayata K, Goda T, Tominaga S, Fukuda N, Nakai T, Nagano S, Ojima T, Kawai M. Kitadani J, et al. Among authors: nakai t. Surg Laparosc Endosc Percutan Tech. 2024 Dec 1;34(6):619-624. doi: 10.1097/SLE.0000000000001331. Surg Laparosc Endosc Percutan Tech. 2024. PMID: 39632426

8

Revision Total Hip Arthroplasty for Spongy Metal Lübeck Hip Prosthesis with Repeated Stem Fracture and Periprosthetic Femur Fractures: A Case Report.

Nakai T, Fukunishi S. Nakai T, et al. Hip Pelvis. 2024 Dec 1;36(4):320-325. doi: 10.5371/hp.2024.36.4.320. Hip Pelvis. 2024. PMID: 39620573 Free PMC article.

9

Erythropoietin Production in Embryonic Neural Cells is Controlled by Hypoxia Signaling and Histone Deacetylases with an Undifferentiated Cellular State.

Iwamura Y, Nakai T, Kato K, Ishioka H, Yamamoto M, Hirano I, Suzuki N. Iwamura Y, et al. Among authors: nakai t. Mol Cell Biol. 2025 Jan;45(1):32-45. doi: 10.1080/10985549.2024.2428717. Epub 2024 Dec 2. Mol Cell Biol. 2025. PMID: 39620278 Free article.

10

Mechanical studies for the rotational stability of a cemented stem in cases with stem anteversion adjustment in the cement mantle.

Goshi A, Takeda Y, Nakai T, Fukunishi S. Goshi A, et al. Among authors: nakai t. J Orthop Sci. 2024 Nov 26:S0949-2658(24)00199-4. doi: 10.1016/j.jos.2024.10.006. Online ahead of print. J Orthop Sci. 2024. PMID: 39603903

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