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Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response.
Ghari F, Quirke AM, Munro S, Kawalkowska J, Picaud S, McGouran J, Subramanian V, Muth A, Williams R, Kessler B, Thompson PR, Fillipakopoulos P, Knapp S, Venables PJ, La Thangue NB. Ghari F, et al. Among authors: la thangue nb. Sci Adv. 2016 Feb 5;2(2):e1501257. doi: 10.1126/sciadv.1501257. eCollection 2016 Feb. Sci Adv. 2016. PMID: 26989780 Free PMC article.
To live or let die - complexity within the E2F1 pathway.
Poppy Roworth A, Ghari F, La Thangue NB. Poppy Roworth A, et al. Among authors: la thangue nb. Mol Cell Oncol. 2015 Jan 30;2(1):e970480. doi: 10.4161/23723548.2014.970480. eCollection 2015 Jan-Mar. Mol Cell Oncol. 2015. PMID: 27308406 Free PMC article. Review.
DNA-damage response control of E2F7 and E2F8.
Zalmas LP, Zhao X, Graham AL, Fisher R, Reilly C, Coutts AS, La Thangue NB. Zalmas LP, et al. Among authors: la thangue nb. EMBO Rep. 2008 Mar;9(3):252-9. doi: 10.1038/sj.embor.7401158. Epub 2008 Jan 18. EMBO Rep. 2008. PMID: 18202719 Free PMC article.
NEDDylation regulates E2F-1-dependent transcription.
Loftus SJ, Liu G, Carr SM, Munro S, La Thangue NB. Loftus SJ, et al. Among authors: la thangue nb. EMBO Rep. 2012 Sep;13(9):811-8. doi: 10.1038/embor.2012.113. Epub 2012 Jul 27. EMBO Rep. 2012. PMID: 22836579 Free PMC article.
HDAC inhibitor-based therapies: can we interpret the code?
New M, Olzscha H, La Thangue NB. New M, et al. Among authors: la thangue nb. Mol Oncol. 2012 Dec;6(6):637-56. doi: 10.1016/j.molonc.2012.09.003. Epub 2012 Oct 23. Mol Oncol. 2012. PMID: 23141799 Free PMC article. Review.
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S. Picaud S, et al. Among authors: la thangue nb. Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9. Cancer Res. 2015. PMID: 26552700 Free PMC article.
163 results