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Page 1
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design.
Enríquez-Flores S, Rodríguez-Romero A, Hernández-Alcántara G, Oria-Hernández J, Gutiérrez-Castrellón P, Pérez-Hernández G, de la Mora-de la Mora I, Castillo-Villanueva A, García-Torres I, Méndez ST, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H. Enríquez-Flores S, et al. Proteins. 2011 Sep;79(9):2711-24. doi: 10.1002/prot.23100. Epub 2011 Jul 22. Proteins. 2011. PMID: 21786322
The active (ADHa) and inactive (ADHi) forms of the PQQ-alcohol dehydrogenase from Gluconacetobacter diazotrophicus differ in their respective oligomeric structures and redox state of their corresponding prosthetic groups.
Gómez-Manzo S, González-Valdez AA, Oria-Hernández J, Reyes-Vivas H, Arreguín-Espinosa R, Kroneck PM, Sosa-Torres ME, Escamilla JE. Gómez-Manzo S, et al. FEMS Microbiol Lett. 2012 Mar;328(2):106-13. doi: 10.1111/j.1574-6968.2011.02487.x. Epub 2012 Jan 6. FEMS Microbiol Lett. 2012. PMID: 22188488
Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Hernández-Alcántara G, Torres-Larios A, Enríquez-Flores S, García-Torres I, Castillo-Villanueva A, Méndez ST, de la Mora-de la Mora I, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H, Oria-Hernández J. Hernández-Alcántara G, et al. PLoS One. 2013 Jul 22;8(7):e69031. doi: 10.1371/journal.pone.0069031. Print 2013. PLoS One. 2013. PMID: 23894402 Free PMC article.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
De La Mora-De La Mora I, Torres-Larios A, Mendoza-Hernández G, Enriquez-Flores S, Castillo-Villanueva A, Mendez ST, Garcia-Torres I, Torres-Arroyo A, Gómez-Manzo S, Marcial-Quino J, Oria-Hernández J, López-Velázquez G, Reyes-Vivas H. De La Mora-De La Mora I, et al. Biochim Biophys Acta. 2013 Dec;1834(12):2702-11. doi: 10.1016/j.bbapap.2013.08.012. Epub 2013 Sep 20. Biochim Biophys Acta. 2013. PMID: 24056040
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Reyes-Vivas H, de la Mora-de la Mora I, Castillo-Villanueva A, Yépez-Mulia L, Hernández-Alcántara G, Figueroa-Salazar R, García-Torres I, Gómez-Manzo S, Méndez ST, Vanoye-Carlo A, Marcial-Quino J, Torres-Arroyo A, Oria-Hernández J, Gutiérrez-Castrellón P, Enríquez-Flores S, López-Velázquez G. Reyes-Vivas H, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7072-82. doi: 10.1128/AAC.02900-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223993 Free PMC article.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Gómez-Manzo S, Terrón-Hernández J, De la Mora-De la Mora I, González-Valdez A, Marcial-Quino J, García-Torres I, Vanoye-Carlo A, López-Velázquez G, Hernández-Alcántara G, Oria-Hernández J, Reyes-Vivas H, Enríquez-Flores S. Gómez-Manzo S, et al. Int J Mol Sci. 2014 Nov 17;15(11):21179-201. doi: 10.3390/ijms151121179. Int J Mol Sci. 2014. PMID: 25407525 Free PMC article.
Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis.
Navarrete-Vázquez G, Chávez-Silva F, Colín-Lozano B, Estrada-Soto S, Hidalgo-Figueroa S, Guerrero-Álvarez J, Méndez ST, Reyes-Vivas H, Oria-Hernández J, Canul-Canché J, Ortiz-Andrade R, Moo-Puc R. Navarrete-Vázquez G, et al. Bioorg Med Chem. 2015 May 1;23(9):2204-10. doi: 10.1016/j.bmc.2015.02.059. Epub 2015 Mar 10. Bioorg Med Chem. 2015. PMID: 25801157
Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.
de la Mora-de la Mora I, Torres-Larios A, Enríquez-Flores S, Méndez ST, Castillo-Villanueva A, Gómez-Manzo S, López-Velázquez G, Marcial-Quino J, Torres-Arroyo A, García-Torres I, Reyes-Vivas H, Oria-Hernández J. de la Mora-de la Mora I, et al. PLoS One. 2015 Apr 17;10(4):e0123379. doi: 10.1371/journal.pone.0123379. eCollection 2015. PLoS One. 2015. PMID: 25884638 Free PMC article.
33 results