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Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice.
Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock C, Panchapakesan U, Forbes JM. Gallo LA, et al. Among authors: harvie bm. Sci Rep. 2016 May 26;6:26428. doi: 10.1038/srep26428. Sci Rep. 2016. PMID: 27226136 Free PMC article.
Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes.
Ward MS, Flemming NB, Gallo LA, Fotheringham AK, McCarthy DA, Zhuang A, Tang PH, Borg DJ, Shaw H, Harvie B, Briskey DR, Roberts LA, Plan MR, Murphy MP, Hodson MP, Forbes JM. Ward MS, et al. Sci Rep. 2017 Nov 9;7(1):15190. doi: 10.1038/s41598-017-15589-x. Sci Rep. 2017. PMID: 29123192 Free PMC article.
Erratum: Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice.
Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock C, Panchapakesan U, Forbes JM. Gallo LA, et al. Among authors: harvie bm. Sci Rep. 2016 Jul 7;6:28124. doi: 10.1038/srep28124. Sci Rep. 2016. PMID: 27389496 Free PMC article. No abstract available.