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Loss of intestinal O-glycans promotes spontaneous duodenal tumors.
Gao N, Bergstrom K, Fu J, Xie B, Chen W, Xia L. Gao N, et al. Among authors: xia l. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G74-83. doi: 10.1152/ajpgi.00060.2016. Epub 2016 May 26. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27229122 Free PMC article.
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice.
Fu J, Gerhardt H, McDaniel JM, Xia B, Liu X, Ivanciu L, Ny A, Hermans K, Silasi-Mansat R, McGee S, Nye E, Ju T, Ramirez MI, Carmeliet P, Cummings RD, Lupu F, Xia L. Fu J, et al. Among authors: xia l, xia b. J Clin Invest. 2008 Nov;118(11):3725-37. doi: 10.1172/JCI36077. Epub 2008 Oct 16. J Clin Invest. 2008. PMID: 18924607 Free PMC article.
Core 1-derived O-glycans are essential E-selectin ligands on neutrophils.
Yago T, Fu J, McDaniel JM, Miner JJ, McEver RP, Xia L. Yago T, et al. Among authors: xia l. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9204-9. doi: 10.1073/pnas.1003110107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439727 Free PMC article.
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice.
Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E, Thomsson KA, McGee S, Mansour L, Tong M, McDaniel JM, Sferra TJ, Turner JR, Chen H, Hansson GC, Braun J, Xia L. Fu J, et al. Among authors: xia l. J Clin Invest. 2011 Apr;121(4):1657-66. doi: 10.1172/JCI45538. Epub 2011 Mar 7. J Clin Invest. 2011. PMID: 21383503 Free PMC article.
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L. Herzog BH, et al. Among authors: xia l. Nature. 2013 Oct 3;502(7469):105-9. doi: 10.1038/nature12501. Epub 2013 Sep 1. Nature. 2013. PMID: 23995678 Free PMC article.
6,802 results