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Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity.
Dos Santos Fernandes GF, de Souza PC, Moreno-Viguri E, Santivañez-Veliz M, Paucar R, Pérez-Silanes S, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Man Chin C, da Silva PB, Chorilli M, Solcia MC, Ribeiro CM, Silva CSP, Marino LB, Bosquesi PL, Hunt DM, de Carvalho LPS, de Souza Costa CA, Cho SH, Wang Y, Franzblau SG, Pavan FR, Dos Santos JL. Dos Santos Fernandes GF, et al. Among authors: marino lb. J Med Chem. 2017 Oct 26;60(20):8647-8660. doi: 10.1021/acs.jmedchem.7b01332. Epub 2017 Oct 16. J Med Chem. 2017. PMID: 28968083 Free PMC article.
Comparison of resazurin microtiter assay performance and BACTEC MGIT 960 in the susceptibility testing of Brazilian clinical isolates of Mycobacterium tuberculosis to four first-line drugs.
Miyata M, Pavan FR, Sato DN, Marino LB, Hirata MH, Cardoso RF, de Melo FA, Leite CQ. Miyata M, et al. Among authors: marino lb. Braz J Microbiol. 2013 May 14;44(1):281-5. doi: 10.1590/S1517-83822013005000028. eCollection 2013. Braz J Microbiol. 2013. PMID: 24159317 Free PMC article.
Furoxan derivatives demonstrated in vivo efficacy by reducing Mycobacterium tuberculosis to undetectable levels in a mouse model of infection.
de Souza PC, Fernandes GFS, Marino LB, Ribeiro CM, Silva PBD, Chorilli M, Silva CSP, Resende FA, Solcia MC, de Grandis RA, Costa CAS, Cho SH, Wang Y, Franzblau SG, Dos Santos JL, Pavan FR. de Souza PC, et al. Among authors: marino lb. Biomed Pharmacother. 2020 Oct;130:110592. doi: 10.1016/j.biopha.2020.110592. Epub 2020 Aug 4. Biomed Pharmacother. 2020. PMID: 32763822 Free article.
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Mori G, Chiarelli LR, Esposito M, Makarov V, Bellinzoni M, Hartkoorn RC, Degiacomi G, Boldrin F, Ekins S, de Jesus Lopes Ribeiro AL, Marino LB, Centárová I, Svetlíková Z, Blaško J, Kazakova E, Lepioshkin A, Barilone N, Zanoni G, Porta A, Fondi M, Fani R, Baulard AR, Mikušová K, Alzari PM, Manganelli R, de Carvalho LP, Riccardi G, Cole ST, Pasca MR. Mori G, et al. Among authors: marino lb. Chem Biol. 2015 Jul 23;22(7):917-27. doi: 10.1016/j.chembiol.2015.05.016. Epub 2015 Jun 18. Chem Biol. 2015. PMID: 26097035 Free PMC article.
Antitubercular activity of Ru (II) isoniazid complexes.
Aguiar Id, Tavares A, Roveda AC Jr, da Silva AC, Marino LB, Lopes ÉO, Pavan FR, Lopes LG, Franco DW. Aguiar Id, et al. Among authors: marino lb. Eur J Pharm Sci. 2015 Apr 5;70:45-54. doi: 10.1016/j.ejps.2015.01.008. Epub 2015 Jan 28. Eur J Pharm Sci. 2015. PMID: 25638418
36 results