Huang L - Search Results

1

Design, synthesis, and biological evaluation of anti-EV71 agents.

Li P, Yang B, Hao F, Wang P, He H, Huang L, Zhang X, Zhang S, Peng X, Yin K, Hu J, Chen X, Gu Z, Wang L, Shen L, Hu G, Li N, Li J, Chen S, Xiao W, Wang Z, Guo Q, Chang X, Zhang L, Cai Q, Lin T. Li P, et al. Among authors: huang l. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3346-3350. doi: 10.1016/j.bmcl.2016.05.036. Epub 2016 May 14. Bioorg Med Chem Lett. 2016. PMID: 27234148

2

Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors.

Huang D, Huang L, Zhang Q, Li J. Huang D, et al. Among authors: huang l. Eur J Med Chem. 2017 Nov 10;140:212-228. doi: 10.1016/j.ejmech.2017.08.060. Epub 2017 Sep 14. Eur J Med Chem. 2017. PMID: 28938137

3

Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR.

Yu T, Li N, Wu C, Guan A, Li Y, Peng Z, He M, Li J, Gong Z, Huang L, Gao B, Hao D, Sun J, Pan Y, Shen L, Chan C, Lu X, Yuan H, Li Y, Li J, Chen S. Yu T, et al. Among authors: huang l. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261. doi: 10.1021/acsmedchemlett.8b00002. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541370 Free PMC article.

4

Discovery and Evaluation of Pyrazolo[3,4-d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor.

Zhang X, Sheng X, Shen J, Zhang S, Sun W, Shen C, Li Y, Wang J, Lv H, Cui M, Zhu Y, Huang L, Hao D, Qi Z, Sun G, Mao W, Pan Y, Shen L, Li X, Hu G, Gong Z, Han S, Li J, Chen S, Tu R, Wang X, Wu C. Zhang X, et al. Among authors: huang l. ACS Med Chem Lett. 2019 Dec 11;11(10):1863-1868. doi: 10.1021/acsmedchemlett.9b00395. eCollection 2020 Oct 8. ACS Med Chem Lett. 2019. PMID: 33062165 Free PMC article.

5

Rational design, synthesis and biological evaluation of dual PARP-1/2 and TNKS1/2 inhibitors for cancer therapy.

Xu Y, Wu H, Huang L, Zhai B, Li X, Xu S, Wu X, Zhu Q, Xu Q. Xu Y, et al. Among authors: huang l. Eur J Med Chem. 2022 Jul 5;237:114417. doi: 10.1016/j.ejmech.2022.114417. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35504210

6

Discovery of Potent and Novel Dual PARP/BRD4 Inhibitors for Efficient Treatment of Pancreatic Cancer.

Wang SP, Li Y, Huang SH, Wu SQ, Gao LL, Sun Q, Lin QW, Huang L, Meng LQ, Zou Y, Zhu QH, Xu YG. Wang SP, et al. Among authors: huang l, huang sh. J Med Chem. 2021 Dec 9;64(23):17413-17435. doi: 10.1021/acs.jmedchem.1c01535. Epub 2021 Nov 23. J Med Chem. 2021. PMID: 34813314

7

Discovery of novel potent covalent inhibitor-based EGFR degrader with excellent in vivo efficacy.

Shi S, Du Y, Huang L, Cui J, Niu J, Xu Y, Zhu Q. Shi S, et al. Among authors: huang l. Bioorg Chem. 2022 Mar;120:105605. doi: 10.1016/j.bioorg.2022.105605. Epub 2022 Jan 10. Bioorg Chem. 2022. PMID: 35081479

8

Bioevaluation of a dual PI3K/HDAC inhibitor for the treatment of diffuse large B-cell lymphoma.

Zhang K, Huang L, Lai F, Lin S, Tian H, Wu D, Chen X, Xu H. Zhang K, et al. Among authors: huang l. Bioorg Med Chem Lett. 2022 Sep 1;71:128825. doi: 10.1016/j.bmcl.2022.128825. Epub 2022 May 27. Bioorg Med Chem Lett. 2022. PMID: 35644299

9

Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy.

Tang Y, Huang S, Chen X, Huang J, Lin Q, Huang L, Wang S, Zhu Q, Xu Y, Zou Y. Tang Y, et al. Among authors: huang l, huang s, huang j. Molecules. 2022 Oct 6;27(19):6637. doi: 10.3390/molecules27196637. Molecules. 2022. PMID: 36235174 Free PMC article.

10

Novel nitric oxide-releasing derivatives of pyranocarbazole as antitumor agents: Design, synthesis, biological evaluation, and nitric oxide release studies.

Zang Y, Huang L, Chen X, Li C, Ma J, Chen X, Zhang D, Lai F. Zang Y, et al. Among authors: huang l. Eur J Med Chem. 2022 Dec 15;244:114832. doi: 10.1016/j.ejmech.2022.114832. Epub 2022 Oct 7. Eur J Med Chem. 2022. PMID: 36270090

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

34,880 results

Search Page

Filters