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Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response.
Chen Z, Cox KS, Tang A, Roman J, Fink M, Kaufhold RM, Guan L, Xie A, Boddicker MA, Mcguinness D, Xiao X, Li H, Skinner JM, Verch T, Retzlaff M, Vora KA. Chen Z, et al. BMC Infect Dis. 2018 Dec 4;18(1):613. doi: 10.1186/s12879-018-3517-7. BMC Infect Dis. 2018. PMID: 30509199 Free PMC article.
Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes.
Xiao X, Tang A, Cox KS, Wen Z, Callahan C, Sullivan NL, Nahas DD, Cosmi S, Galli JD, Minnier M, Verma D, Babaoglu K, Su H, Bett AJ, Vora KA, Chen Z, Zhang L. Xiao X, et al. Among authors: chen z. MAbs. 2019 Nov-Dec;11(8):1415-1427. doi: 10.1080/19420862.2019.1654304. Epub 2019 Aug 23. MAbs. 2019. PMID: 31402751 Free PMC article.
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Tang A, Chen Z, Cox KS, Su HP, Callahan C, Fridman A, Zhang L, Patel SB, Cejas PJ, Swoyer R, Touch S, Citron MP, Govindarajan D, Luo B, Eddins M, Reid JC, Soisson SM, Galli J, Wang D, Wen Z, Heidecker GJ, Casimiro DR, DiStefano DJ, Vora KA. Tang A, et al. Among authors: chen z. Nat Commun. 2019 Sep 12;10(1):4153. doi: 10.1038/s41467-019-12137-1. Nat Commun. 2019. PMID: 31515478 Free PMC article.
Development of a microneutralization assay for HSV-2.
Horton MS, Minnier M, Cosmi S, Cox K, Galli J, Peters J, Sullivan N, Squadroni B, Tang A, Fridman A, Wang D, Chen Z, Vora KA. Horton MS, et al. Among authors: chen z. J Virol Methods. 2021 Nov;297:114268. doi: 10.1016/j.jviromet.2021.114268. Epub 2021 Aug 24. J Virol Methods. 2021. PMID: 34437874
Profiling of hMPV F-specific antibodies isolated from human memory B cells.
Xiao X, Fridman A, Zhang L, Pristatsky P, Durr E, Minnier M, Tang A, Cox KS, Wen Z, Moore R, Tian D, Galli JD, Cosmi S, Eddins MJ, Sullivan NL, Yan X, Bett AJ, Su HP, Vora KA, Chen Z, Zhang L. Xiao X, et al. Among authors: chen z. Nat Commun. 2022 May 10;13(1):2546. doi: 10.1038/s41467-022-30205-x. Nat Commun. 2022. PMID: 35538099 Free PMC article.
Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
Xiao X, Wen Z, Chen Q, Shipman JM, Kostas J, Reid JC, Warren C, Tang A, Luo B, O'Donnell G, Fridman A, Chen Z, Vora KA, Zhang L, Su H-P, Eddins MJ. Xiao X, et al. Among authors: chen z, chen q. J Virol. 2023 Dec 21;97(12):e0105223. doi: 10.1128/jvi.01052-23. Epub 2023 Nov 30. J Virol. 2023. PMID: 38032197 Free PMC article.
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