Tunçman G - Search Results

1

An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease.

Burak MF, Tuncman G, Ayci AN, Chetal K, Seropian GYL, Inouye K, Lai ZW, Dagtekin N, Sadreyev RI, Israel E, Hotamışlıgil GS. Burak MF, et al. Among authors: tuncman g. bioRxiv [Preprint]. 2024 Jul 18:2024.07.15.603433. doi: 10.1101/2024.07.15.603433. bioRxiv. 2024. PMID: 39071372 Free PMC article. Preprint.

2

Author Correction: A central role for JNK in obesity and insulin resistance.

Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. Hirosumi J, et al. Among authors: tuncman g. Nature. 2023 Jul;619(7968):E25. doi: 10.1038/s41586-023-06285-0. Nature. 2023. PMID: 37328696 No abstract available.

3

Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism.

Tirosh A, Tuncman G, Calay ES, Rathaus M, Ron I, Tirosh A, Yalcin A, Lee YG, Livne R, Ron S, Minsky N, Arruda AP, Hotamisligil GS. Tirosh A, et al. Among authors: tuncman g. Cell Metab. 2021 Aug 3;33(8):1716. doi: 10.1016/j.cmet.2021.07.005. Cell Metab. 2021. PMID: 34348100 Free PMC article. No abstract available.

4

Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism.

Tirosh A, Tuncman G, Calay ES, Rathaus M, Ron I, Tirosh A, Yalcin A, Lee YG, Livne R, Ron S, Minsky N, Arruda AP, Hotamisligil GS. Tirosh A, et al. Among authors: tuncman g. Cell Metab. 2021 Feb 2;33(2):319-333.e6. doi: 10.1016/j.cmet.2020.11.009. Epub 2020 Dec 18. Cell Metab. 2021. PMID: 33340456 Free PMC article.

5

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.

Tirosh A, Calay ES, Tuncman G, Claiborn KC, Inouye KE, Eguchi K, Alcala M, Rathaus M, Hollander KS, Ron I, Livne R, Heianza Y, Qi L, Shai I, Garg R, Hotamisligil GS. Tirosh A, et al. Among authors: tuncman g. Sci Transl Med. 2019 Apr 24;11(489):eaav0120. doi: 10.1126/scitranslmed.aav0120. Sci Transl Med. 2019. PMID: 31019023

6

Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.

Burak MF, Inouye KE, White A, Lee A, Tuncman G, Calay ES, Sekiya M, Tirosh A, Eguchi K, Birrane G, Lightwood D, Howells L, Odede G, Hailu H, West S, Garlish R, Neale H, Doyle C, Moore A, Hotamisligil GS. Burak MF, et al. Among authors: tuncman g. Sci Transl Med. 2015 Dec 23;7(319):319ra205. doi: 10.1126/scitranslmed.aac6336. Epub 2015 Dec 23. Sci Transl Med. 2015. PMID: 26702093

7

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS. Cao H, et al. Among authors: tuncman g. Cell Metab. 2013 May 7;17(5):768-78. doi: 10.1016/j.cmet.2013.04.012. Cell Metab. 2013. PMID: 23663740 Free PMC article.

8

Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis.

Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS. Nakamura T, et al. Among authors: tuncman g. Cell. 2010 Feb 5;140(3):338-48. doi: 10.1016/j.cell.2010.01.001. Cell. 2010. PMID: 20144759 Free PMC article.

9

Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.

Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS. Furuhashi M, et al. Among authors: tuncman g. J Clin Invest. 2008 Jul;118(7):2640-50. doi: 10.1172/JCI34750. J Clin Invest. 2008. PMID: 18551191 Free PMC article.

10

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.

Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS. Furuhashi M, et al. Among authors: tuncman g. Nature. 2007 Jun 21;447(7147):959-65. doi: 10.1038/nature05844. Epub 2007 Jun 6. Nature. 2007. PMID: 17554340 Free PMC article.

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