Hughes CS - Search Results

1

Purification of bacterial membrane sensor kinases and biophysical methods for determination of their ligand and inhibitor interactions.

Hussain R, Harding SE, Hughes CS, Ma P, Patching SG, Edara S, Siligardi G, Henderson PJ, Phillips-Jones MK. Hussain R, et al. Among authors: hughes cs. Biochem Soc Trans. 2016 Jun 15;44(3):810-23. doi: 10.1042/BST20160023. Biochem Soc Trans. 2016. PMID: 27284046 Free PMC article. Review.

2

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin.

Phillips-Jones MK, Channell G, Kelsall CJ, Hughes CS, Ashcroft AE, Patching SG, Dinu V, Gillis RB, Adams GG, Harding SE. Phillips-Jones MK, et al. Among authors: hughes cs. Sci Rep. 2017 Apr 11;7:46180. doi: 10.1038/srep46180. Sci Rep. 2017. PMID: 28397853 Free PMC article.

3

Characterisation of sensor kinase by CD spectroscopy: golden rules and tips.

Siligardi G, Hughes CS, Hussain R. Siligardi G, et al. Among authors: hughes cs. Biochem Soc Trans. 2018 Dec 17;46(6):1627-1642. doi: 10.1042/BST20180222. Epub 2018 Dec 4. Biochem Soc Trans. 2018. PMID: 30514767 Free PMC article. Review.

4

Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci.

Hughes CS, Longo E, Phillips-Jones MK, Hussain R. Hughes CS, et al. Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):1951-1959. doi: 10.1016/j.bbagen.2017.05.011. Epub 2017 May 13. Biochim Biophys Acta Gen Subj. 2017. PMID: 28511809 Free PMC article.

5

Quality control and biophysical characterisation data of VanS_A.

Hughes CS, Longo E, Phillips-Jones MK, Hussain R. Hughes CS, et al. Data Brief. 2017 Jul 13;14:41-47. doi: 10.1016/j.dib.2017.07.012. eCollection 2017 Oct. Data Brief. 2017. PMID: 28765830 Free PMC article.

6

To Boil an Egg: Substrate Binding Affects Critical Stability in Thermal Unfolding of Proteins.

Hussain R, Hughes CS, Jávorfi T, Siligardi G, Williams P, Bonev BB. Hussain R, et al. Among authors: hughes cs. J Phys Chem B. 2018 Mar 1;122(8):2213-2218. doi: 10.1021/acs.jpcb.7b10643. Epub 2018 Feb 15. J Phys Chem B. 2018. PMID: 29401389 Free article.

7

The gelatinase biosynthesis-activating pheromone binds and stabilises the FsrB membrane protein in Enterococcus faecalis quorum sensing.

Littlewood S, Tattersall H, Hughes CS, Hussain R, Ma P, Harding SE, Nakayama J, Phillips-Jones MK. Littlewood S, et al. Among authors: hughes cs. FEBS Lett. 2020 Feb;594(3):553-563. doi: 10.1002/1873-3468.13634. Epub 2019 Oct 21. FEBS Lett. 2020. PMID: 31598959 Free PMC article.

8

Enzyme-Ligand Interaction Monitored by Synchrotron Radiation Circular Dichroism.

Hussain R, Hughes CS, Siligardi G. Hussain R, et al. Among authors: hughes cs. Methods Mol Biol. 2020;2089:87-118. doi: 10.1007/978-1-0716-0163-1_6. Methods Mol Biol. 2020. PMID: 31773649

9

Correction To: Enzyme-Ligand Interaction Monitored by Synchrotron Radiation Circular Dichroism.

Hussain R, Hughes CS, Siligardi G. Hussain R, et al. Among authors: hughes cs. Methods Mol Biol. 2020;2089:C1. doi: 10.1007/978-1-0716-0163-1_19. Methods Mol Biol. 2020. PMID: 32157659

10

Spectroscopy data of ceftriaxone-lysozyme interaction and computational studies.

Ruzza P, Vitale RM, Hussain R, Montini A, Honisch C, Pozzebon A, Hughes CS, Biondi B, Amodeo P, Sechi G, Siligardi G. Ruzza P, et al. Among authors: hughes cs. Data Brief. 2018 Apr 30;18:1808-1818. doi: 10.1016/j.dib.2018.04.079. eCollection 2018 Jun. Data Brief. 2018. PMID: 29904682 Free PMC article.

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