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Germline mutations of BRCA1 gene exon 11 are not associated with platinum response neither with survival advantage in patients with primary ovarian cancer: understanding the clinical importance of one of the biggest human exons. A study of the Tumor Bank Ovarian Cancer (TOC) Consortium.
Dimitrova D, Ruscito I, Olek S, Richter R, Hellwag A, Türbachova I, Woopen H, Baron U, Braicu EI, Sehouli J. Dimitrova D, et al. Among authors: hellwag a. Tumour Biol. 2016 Sep;37(9):12329-12337. doi: 10.1007/s13277-016-5109-8. Epub 2016 Jun 14. Tumour Biol. 2016. PMID: 27297669
The cellular ratio of immune tolerance (immunoCRIT) is a definite marker for aggressiveness of solid tumors and may explain tumor dissemination patterns.
Türbachova I, Schwachula T, Vasconcelos I, Mustea A, Baldinger T, Jones KA, Bujard H, Olek A, Olek K, Gellhaus K, Braicu I, Könsgen D, Fryer C, Ravot E, Hellwag A, Westerfeld N, Gruss OJ, Meissner M, Hasan MT, Weber M, Hoffmüller U, Zimmermann S, Loddenkemper C, Mahner S, Babel N, Berns E, Adams R, Zeilinger R, Baron U, Vergote I, Maughan T, Marme F, Dickhaus T, Sehouli J, Olek S. Türbachova I, et al. Among authors: hellwag a. Epigenetics. 2013 Nov;8(11):1226-35. doi: 10.4161/epi.26334. Epub 2013 Sep 26. Epigenetics. 2013. PMID: 24071829 Free article.
DNA methylation analysis as a tool for cell typing.
Baron U, Türbachova I, Hellwag A, Eckhardt F, Berlin K, Hoffmuller U, Gardina P, Olek S. Baron U, et al. Among authors: hellwag a. Epigenetics. 2006 Jan-Mar;1(1):55-60. doi: 10.4161/epi.1.1.2643. Epub 2006 Feb 25. Epigenetics. 2006. PMID: 17998806 Free article.