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Substitution of blood coagulation factor X-binding to Ad5 by position-specific PEGylation: Preventing vector clearance and preserving infectivity.
J Control Release. 2016 Aug 10;235:379-392. doi: 10.1016/j.jconrel.2016.06.022. Epub 2016 Jun 11.
J Control Release. 2016.
PMID: 27302248
Free article.
Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cells.
Prill JM, Espenlaub S, Samen U, Engler T, Schmidt E, Vetrini F, Rosewell A, Grove N, Palmer D, Ng P, Kochanek S, Kreppel F.
Prill JM, et al.
Mol Ther. 2011 Jan;19(1):83-92. doi: 10.1038/mt.2010.229. Epub 2010 Oct 19.
Mol Ther. 2011.
PMID: 20959811
Free PMC article.
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Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo.
Prill JM, Subr V, Pasquarelli N, Engler T, Hoffmeister A, Kochanek S, Ulbrich K, Kreppel F.
Prill JM, et al.
PLoS One. 2014 Jan 27;9(1):e82716. doi: 10.1371/journal.pone.0082716. eCollection 2014.
PLoS One. 2014.
PMID: 24475024
Free PMC article.
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