Jakubowski JA - Search Results

1

The active metabolite of prasugrel, R-138727, improves cerebral blood flow and reduces cerebral infarction and neurologic deficits in a non-human primate model of acute ischaemic stroke.

Sugidachi A, Mizuno M, Ohno K, Jakubowski JA, Tomizawa A. Sugidachi A, et al. Among authors: jakubowski ja. Eur J Pharmacol. 2016 Oct 5;788:132-139. doi: 10.1016/j.ejphar.2016.06.023. Epub 2016 Jun 16. Eur J Pharmacol. 2016. PMID: 27318323

2

The influence of P2Y12 receptor deficiency on the platelet inhibitory activities of prasugrel in a mouse model: evidence for specific inhibition of P2Y12 receptors by prasugrel.

Hashimoto M, Sugidachi A, Isobe T, Niitsu Y, Ogawa T, Jakubowski JA, Asai F. Hashimoto M, et al. Among authors: jakubowski ja. Biochem Pharmacol. 2007 Oct 1;74(7):1003-9. doi: 10.1016/j.bcp.2007.06.027. Epub 2007 Jun 23. Biochem Pharmacol. 2007. PMID: 17681285

3

Repeat oral dosing of prasugrel, a novel P2Y12 receptor inhibitor, results in cumulative and potent antiplatelet and antithrombotic activity in several animal species.

Niitsu Y, Sugidachi A, Ogawa T, Jakubowski JA, Hashimoto M, Isobe T, Otsuguro K, Asai F. Niitsu Y, et al. Among authors: jakubowski ja. Eur J Pharmacol. 2008 Jan 28;579(1-3):276-82. doi: 10.1016/j.ejphar.2007.10.005. Epub 2007 Oct 11. Eur J Pharmacol. 2008. PMID: 17996866

4

Effects of prasugrel, a novel P2Y(12) inhibitor, in rat models of cerebral and peripheral artery occlusive diseases.

Ogawa T, Hashimoto M, Niitsu Y, Jakubowski JA, Tani Y, Otsuguro K, Asai F, Sugidachi A. Ogawa T, et al. Among authors: jakubowski ja. Eur J Pharmacol. 2009 Jun 10;612(1-3):29-34. doi: 10.1016/j.ejphar.2009.03.073. Epub 2009 Apr 6. Eur J Pharmacol. 2009. PMID: 19356727

5

Selective blockade of P2Y12 receptors by prasugrel inhibits myocardial infarction induced by thrombotic coronary artery occlusion in rats.

Sugidachi A, Yamaguchi S, Jakubowski JA, Ohno K, Tomizawa A, Hashimoto M, Niitsu Y. Sugidachi A, et al. Among authors: jakubowski ja. J Cardiovasc Pharmacol. 2011 Sep;58(3):329-34. doi: 10.1097/FJC.0b013e3182244a6f. J Cardiovasc Pharmacol. 2011. PMID: 21697729

6

Comparison of antiplatelet effects of prasugrel and ticagrelor in cynomolgus monkeys by an ELISA-based VASP phosphorylation assay and platelet aggregation.

Tomizawa A, Ohno K, Jakubowski JA, Mizuno M, Sugidachi A. Tomizawa A, et al. Among authors: jakubowski ja. Thromb Haemost. 2013 Oct;110(4):769-76. doi: 10.1160/TH13-03-0260. Epub 2013 Aug 1. Thromb Haemost. 2013. PMID: 23903326

7

Platelet activation biomarkers in Berkeley sickle cell mice and the response to prasugrel.

Ohno K, Tanaka H, Samata N, Jakubowski JA, Tomizawa A, Mizuno M, Sugidachi A. Ohno K, et al. Among authors: jakubowski ja. Thromb Res. 2014 Oct;134(4):889-94. doi: 10.1016/j.thromres.2014.07.035. Epub 2014 Aug 6. Thromb Res. 2014. PMID: 25130912

8

Characterization of platelet aggregation responses in microminipigs: Comparison with miniature pigs and the influence of dual antiplatelet administration of aspirin plus prasugrel.

Ohno K, Tomizawa A, Jakubowski JA, Mizuno M, Sugidachi A. Ohno K, et al. Among authors: jakubowski ja. Thromb Res. 2015 May;135(5):933-8. doi: 10.1016/j.thromres.2015.02.014. Epub 2015 Feb 21. Thromb Res. 2015. PMID: 25776467

9

Prasugrel reduces ischaemic infarct volume and ameliorates neurological deficits in a non-human primate model of middle cerebral artery thrombosis.

Tomizawa A, Ohno K, Jakubowski JA, Mizuno M, Sugidachi A. Tomizawa A, et al. Among authors: jakubowski ja. Thromb Res. 2015 Dec;136(6):1224-30. doi: 10.1016/j.thromres.2015.09.013. Epub 2015 Sep 11. Thromb Res. 2015. PMID: 26388120

10

Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice.

Ohno K, Tomizawa A, Jakubowski JA, Mizuno M, Sugidachi A. Ohno K, et al. Among authors: jakubowski ja. Thromb Res. 2015 Dec;136(6):1245-51. doi: 10.1016/j.thromres.2015.10.010. Epub 2015 Oct 9. Thromb Res. 2015. PMID: 26489728

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