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TIGIT signaling restores suppressor function of Th1 Tregs.
Lucca LE, Axisa PP, Singer ER, Nolan NM, Dominguez-Villar M, Hafler DA. Lucca LE, et al. Among authors: axisa pp. JCI Insight. 2019 Feb 7;4(3):e124427. doi: 10.1172/jci.insight.124427. JCI Insight. 2019. PMID: 30728325 Free PMC article.
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation.
Pichler AC, Carrié N, Cuisinier M, Ghazali S, Voisin A, Axisa PP, Tosolini M, Mazzotti C, Golec DP, Maheo S, do Souto L, Ekren R, Blanquart E, Lemaitre L, Feliu V, Joubert MV, Cannons JL, Guillerey C, Avet-Loiseau H, Watts TH, Salomon BL, Joffre O, Grinberg-Bleyer Y, Schwartzberg PL, Lucca LE, Martinet L. Pichler AC, et al. Among authors: axisa pp. Immunity. 2023 Jul 11;56(7):1631-1648.e10. doi: 10.1016/j.immuni.2023.06.007. Epub 2023 Jun 30. Immunity. 2023. PMID: 37392737 Free PMC article.
Podoplanin is a negative regulator of Th17 inflammation.
Nylander AN, Ponath GD, Axisa PP, Mubarak M, Tomayko M, Kuchroo VK, Pitt D, Hafler DA. Nylander AN, et al. Among authors: axisa pp. JCI Insight. 2017 Sep 7;2(17):e92321. doi: 10.1172/jci.insight.92321. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878118 Free PMC article.
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells.
Sumida TS, Dulberg S, Schupp J, Stillwell HA, Axisa PP, Comi M, Lincoln M, Unterman A, Kaminski N, Madi A, Kuchroo VK, Hafler DA. Sumida TS, et al. Among authors: axisa pp. bioRxiv [Preprint]. 2020 Oct 31:2020.10.30.362947. doi: 10.1101/2020.10.30.362947. bioRxiv. 2020. Update in: Nat Immunol. 2022 Apr;23(4):632-642. doi: 10.1038/s41590-022-01152-y PMID: 33140047 Free PMC article. Updated. Preprint.
20 results