Quach HP - Search Results

1

Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters.

Chow EC, Wang JZ, Quach HP, Tang H, Evans DC, Li AP, Silva J, Pang KS. Chow EC, et al. Among authors: quach hp. Drug Metab Dispos. 2016 Sep;44(9):1524-35. doi: 10.1124/dmd.116.070060. Epub 2016 Jun 24. Drug Metab Dispos. 2016. PMID: 27342868

2

Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice.

Ramakrishnan V, Yang QJ, Quach HP, Cao Y, Chow EC, Mager DE, Pang KS. Ramakrishnan V, et al. Among authors: quach hp. Drug Metab Dispos. 2016 Feb;44(2):189-208. doi: 10.1124/dmd.115.067033. Epub 2015 Nov 19. Drug Metab Dispos. 2016. PMID: 26586377

3

Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models.

Chow EC, Quach HP, Zhang Y, Wang JZ, Evans DC, Li AP, Silva J, Tirona RG, Lai Y, Pang KS. Chow EC, et al. Among authors: quach hp. J Pharmacol Exp Ther. 2017 Jan;360(1):174-191. doi: 10.1124/jpet.116.236935. Epub 2016 Oct 27. J Pharmacol Exp Ther. 2017. PMID: 27789682

4

Highlighting Vitamin D Receptor-Targeted Activities of 1α,25-Dihydroxyvitamin D₃ in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling.

Yang QJ, Bukuroshi P, Quach HP, Chow ECY, Pang KS. Yang QJ, et al. Among authors: quach hp. Drug Metab Dispos. 2018 Jan;46(1):75-87. doi: 10.1124/dmd.117.077271. Epub 2017 Oct 30. Drug Metab Dispos. 2018. PMID: 29084783

5

Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.

Quach HP, Noh K, Hoi SY, Bruinsma A, Groothuis GMM, Li AP, Chow ECY, Pang KS. Quach HP, et al. Biopharm Drug Dispos. 2018 Feb;39(2):99-115. doi: 10.1002/bdd.2118. Epub 2018 Jan 30. Biopharm Drug Dispos. 2018. PMID: 29243851

6

Potencies of vitamin D analogs, 1α-hydroxyvitamin D₃ , 1α-hydroxyvitamin D₂ and 25-hydroxyvitamin D₃ , in lowering cholesterol in hypercholesterolemic mice in vivo.

Quach HP, Dzekic T, Bukuroshi P, Pang KS. Quach HP, et al. Biopharm Drug Dispos. 2018 Apr;39(4):196-204. doi: 10.1002/bdd.2126. Biopharm Drug Dispos. 2018. PMID: 29488238

7

Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D₃ kinetics for extrapolation from mouse to man: Commentary.

Noh K, Yang QJ, Sekhon L, Quach HP, Chow ECY, Pang KS. Noh K, et al. Among authors: quach hp. Biopharm Drug Dispos. 2020 Mar;41(3):126-148. doi: 10.1002/bdd.2223. Biopharm Drug Dispos. 2020. PMID: 32319119

8

Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters.

Noh K, Chow ECY, Quach HP, Groothuis GMM, Tirona RG, Pang KS. Noh K, et al. Among authors: quach hp. AAPS J. 2022 Jun 1;24(4):71. doi: 10.1208/s12248-022-00719-9. AAPS J. 2022. PMID: 35650371 Review.

9

Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.

Chow EC, Quach HP, Vieth R, Pang KS. Chow EC, et al. Among authors: quach hp. Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E977-89. doi: 10.1152/ajpendo.00489.2012. Epub 2013 Mar 12. Am J Physiol Endocrinol Metab. 2013. PMID: 23482451 Free article.

10

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.

Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS. Chow EC, et al. Among authors: quach hp. Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21. Gastroenterology. 2014. PMID: 24365583

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