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Recon 2.2: from reconstruction to model of human metabolism.
Swainston N, Smallbone K, Hefzi H, Dobson PD, Brewer J, Hanscho M, Zielinski DC, Ang KS, Gardiner NJ, Gutierrez JM, Kyriakopoulos S, Lakshmanan M, Li S, Liu JK, Martínez VS, Orellana CA, Quek LE, Thomas A, Zanghellini J, Borth N, Lee DY, Nielsen LK, Kell DB, Lewis NE, Mendes P. Swainston N, et al. Among authors: borth n. Metabolomics. 2016;12:109. doi: 10.1007/s11306-016-1051-4. Epub 2016 Jun 7. Metabolomics. 2016. PMID: 27358602 Free PMC article.
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. Hefzi H, et al. Among authors: borth n. Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020. Cell Syst. 2016. PMID: 27883890 Free PMC article.
What can mathematical modelling say about CHO metabolism and protein glycosylation?
Galleguillos SN, Ruckerbauer D, Gerstl MP, Borth N, Hanscho M, Zanghellini J. Galleguillos SN, et al. Among authors: borth n. Comput Struct Biotechnol J. 2017 Jan 28;15:212-221. doi: 10.1016/j.csbj.2017.01.005. eCollection 2017. Comput Struct Biotechnol J. 2017. PMID: 28228925 Free PMC article. Review.
A reference genome of the Chinese hamster based on a hybrid assembly strategy.
Rupp O, MacDonald ML, Li S, Dhiman H, Polson S, Griep S, Heffner K, Hernandez I, Brinkrolf K, Jadhav V, Samoudi M, Hao H, Kingham B, Goesmann A, Betenbaugh MJ, Lewis NE, Borth N, Lee KH. Rupp O, et al. Among authors: borth n. Biotechnol Bioeng. 2018 Aug;115(8):2087-2100. doi: 10.1002/bit.26722. Epub 2018 May 29. Biotechnol Bioeng. 2018. PMID: 29704459 Free PMC article.
144 results