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Recon 2.2: from reconstruction to model of human metabolism.
Swainston N, Smallbone K, Hefzi H, Dobson PD, Brewer J, Hanscho M, Zielinski DC, Ang KS, Gardiner NJ, Gutierrez JM, Kyriakopoulos S, Lakshmanan M, Li S, Liu JK, Martínez VS, Orellana CA, Quek LE, Thomas A, Zanghellini J, Borth N, Lee DY, Nielsen LK, Kell DB, Lewis NE, Mendes P. Swainston N, et al. Among authors: mendes p. Metabolomics. 2016;12:109. doi: 10.1007/s11306-016-1051-4. Epub 2016 Jun 7. Metabolomics. 2016. PMID: 27358602 Free PMC article.
Channelling can decrease pool size.
Mendes P, Kell DB, Westerhoff HV. Mendes P, et al. Eur J Biochem. 1992 Feb 15;204(1):257-66. doi: 10.1111/j.1432-1033.1992.tb16632.x. Eur J Biochem. 1992. PMID: 1740137 Free article.
Why and when channelling can decrease pool size at constant net flux in a simple dynamic channel.
Mendes P, Kell DB, Westerhoff HV. Mendes P, et al. Biochim Biophys Acta. 1996 Mar 15;1289(2):175-86. doi: 10.1016/0304-4165(95)00152-2. Biochim Biophys Acta. 1996. PMID: 8600971
Biochem. 213, 87-92) have suggested that simulation results peviously published by us (Mendes, P., Kell, D.B. and Westerhoff, H.V. (1992) Eur. J. Biochem. 204, 255-266) which had demonstrated that large reductions of intermediate pool sizes could be accompanied by i …
Biochem. 213, 87-92) have suggested that simulation results peviously published by us (Mendes, P., Kell, D.B. and Westerhoff, …
553 results