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MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma.
Bell JB, Eckerdt FD, Alley K, Magnusson LP, Hussain H, Bi Y, Arslan AD, Clymer J, Alvarez AA, Goldman S, Cheng SY, Nakano I, Horbinski C, Davuluri RV, James CD, Platanias LC. Bell JB, et al. Among authors: goldman s. Mol Cancer Res. 2016 Oct;14(10):984-993. doi: 10.1158/1541-7786.MCR-16-0172. Epub 2016 Jun 30. Mol Cancer Res. 2016. PMID: 27364770 Free PMC article.
REST is a novel prognostic factor and therapeutic target for medulloblastoma.
Taylor P, Fangusaro J, Rajaram V, Goldman S, Helenowski IB, MacDonald T, Hasselblatt M, Riedemann L, Laureano A, Cooper L, Gopalakrishnan V. Taylor P, et al. Among authors: goldman s. Mol Cancer Ther. 2012 Aug;11(8):1713-1723. doi: 10.1158/1535-7163.MCT-11-0990. Epub 2012 Jul 30. Mol Cancer Ther. 2012. PMID: 22848092 Free PMC article.
Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD. Hashizume R, et al. Among authors: goldman s. Neuro Oncol. 2016 Nov;18(11):1519-1528. doi: 10.1093/neuonc/now106. Epub 2016 Jul 1. Neuro Oncol. 2016. PMID: 27370397 Free PMC article.
Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.
Bell JB, Eckerdt F, Dhruv HD, Finlay D, Peng S, Kim S, Kroczynska B, Beauchamp EM, Alley K, Clymer J, Goldman S, Cheng SY, James CD, Nakano I, Horbinski C, Mazar AP, Vuori K, Kumthekar P, Raizer J, Berens ME, Platanias LC. Bell JB, et al. Among authors: goldman s. Mol Cancer Res. 2018 Jan;16(1):32-46. doi: 10.1158/1541-7786.MCR-17-0397. Epub 2017 Oct 17. Mol Cancer Res. 2018. PMID: 29042487 Free PMC article.
Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma.
Eckerdt F, Bell JB, Beauchamp EM, Clymer J, Blyth GT, Kosciuczuk EM, Ma Q, Chen DZ, Horbinski C, Goldman S, Munshi HG, Hashizume R, Platanias LC. Eckerdt F, et al. Among authors: goldman s. Mol Cancer Res. 2019 Jun;17(6):1305-1315. doi: 10.1158/1541-7786.MCR-18-1193. Epub 2019 Mar 6. Mol Cancer Res. 2019. PMID: 30842251 Free PMC article.
2,306 results