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Page 1
Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort.
Löf C, Patyra K, Kuulasmaa T, Vangipurapu J, Undeutsch H, Jaeschke H, Pajunen T, Kero A, Krude H, Biebermann H, Kleinau G, Kühnen P, Rantakari K, Miettinen P, Kirjavainen T, Pursiheimo JP, Mustila T, Jääskeläinen J, Ojaniemi M, Toppari J, Ignatius J, Laakso M, Kero J. Löf C, et al. Among authors: jaeschke h. Thyroid. 2016 Sep;26(9):1215-24. doi: 10.1089/thy.2016.0016. Epub 2016 Aug 2. Thyroid. 2016. PMID: 27373559 Free PMC article.
Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function.
Patyra K, Löf C, Jaeschke H, Undeutsch H, Zheng HS, Tyystjärvi S, Puławska K, Doroszko M, Chruściel M, Loo BM, Kurkijärvi R, Zhang FP, Huang CJ, Ohlsson C, Kero A, Poutanen M, Toppari J, Paschke R, Rahman N, Huhtaniemi I, Jääskeläinen J, Kero J. Patyra K, et al. Among authors: jaeschke h. Thyroid. 2022 Apr;32(4):459-471. doi: 10.1089/thy.2021.0535. Thyroid. 2022. PMID: 35044245 Free PMC article.
Partial thyrocyte-specific Gαs deficiency leads to rapid-onset hypothyroidism, hyperplasia, and papillary thyroid carcinoma-like lesions in mice.
Patyra K, Jaeschke H, Löf C, Jännäri M, Ruohonen ST, Undeutsch H, Khalil M, Kero A, Poutanen M, Toppari J, Chen M, Weinstein LS, Paschke R, Kero J. Patyra K, et al. Among authors: jaeschke h. FASEB J. 2018 May 25:fj201800211R. doi: 10.1096/fj.201800211R. Online ahead of print. FASEB J. 2018. PMID: 29799790
Thus, these mice are a novel model to elucidate the pathophysiological consequences of hypothyroidism and TSHR/G(s)/cAMP-mediated tumorigenesis.-Patyra, K., Jaeschke, H., Lof, C., Jannari, M., Ruohonen, S. T., Undeutsch, H., Khalil, M., Kero, A., Poutanen, M. …
Thus, these mice are a novel model to elucidate the pathophysiological consequences of hypothyroidism and TSHR/G(s)/cAMP-mediated tumorigene …
475 results